Watchful waiting or TAVR for moderate aortic valve narrowing
Part of Heart & circulation clinical trials.
This study compares regular monitoring (“clinical surveillance”) versus replacing the aortic valve using a minimally invasive procedure called TAVR for people with moderate aortic stenosis. It aims to see which approach better reduces symptoms or heart damage over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older when you would join the study
- You have moderate aortic stenosis (a narrowed aortic valve)
- You have symptoms or signs your heart is already being affected (damage or reduced function)
- Your study team can clearly explain the study, and you agree in writing
- You do not have heart/aortic valve anatomy that makes TAVR unsafe through the groin route
- You do not have certain valve types or severe related problems (like a severely leaky valve or severe prior valve treatment)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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