Brain stimulation to help people quit smoking
Part of Mental health clinical trials.
This study tests whether a type of brain stimulation (rTMS) can help people stop smoking. It targets brain circuits involved in cravings, aiming to support quitting safely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 22 and 70 years old.
- You currently smoke at least 10 cigarettes per day and have a recent-smoking carbon monoxide level over 10 ppm.
- You haven’t had substance-abuse treatment in the last 30 days.
- Your smoking fits “tobacco use disorder” based on DSM-5, and you’re in generally stable health.
- If you’re female, you can’t be pregnant and you’ll use reliable birth control.
- You must be willing to get an MRI and be able to lie still; no metal in your head/scanner safety issues and no strong claustrophobia.
- You’re motivated to quit (you answer “very likely” or “somewhat likely” on the quit-motivation questions).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a personalized brain stimulation treatment to help veterans quit smoking. It uses magnetic pulses to target brain areas involved in addiction, which may reduce cravings and make it easier to stop.
This trial tests different targets for repetitive transcranial magnetic stimulation (rTMS)—a non-surgical brain stimulation—to change brain “reward” activity in people who are nicotine dependent. If you qualify, you may receive sessions of brain stimulation as the researchers look for the best brain target.
This study tests whether a non-invasive brain stimulation technique (rTMS) combined with a behavioral task can reduce your craving to smoke. It might help if you smoke regularly and want to cut back.
This study tests whether a brain stimulation treatment called rTMS can help people with psychiatric conditions quit smoking. You will be randomly assigned to get either rTMS or a nicotine patch, and your progress will be tracked to see which treatment works better.
This study tests whether a non-invasive brain stimulation technique (rTMS) can help people who smoke reduce cravings or change smoking behavior. You'll also have your brain activity recorded with a cap (EEG) and do some vaping tasks.
This trial tests if a type of brain stimulation (TMS) can help people with nicotine dependence reduce cravings. It may be an option if you smoke or use e-cigarettes heavily and want to understand how your brain responds to treatment.
Hear when a new Tobacco Use trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.