Clin2
NCT05006716Possibly a fitRecruiting

New treatment for blood cancers that have returned

B-cell MalignancyMarginal Zone LymphomaFollicular LymphomaNon-Hodgkin LymphomaWaldenström MacroglobulinemiaChronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaMantle Cell Lymphoma

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.

This trial tests a new pill, tacabrutideg, for blood cancers that have returned or not improved after earlier treatments. It may work for patients who have already tried a type of targeted therapy called a BTK inhibitor.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
689 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a type of blood cancer such as CLL/SLL, follicular lymphoma, mantle cell lymphoma, or certain other lymphomas.
  • Your cancer has come back or has not improved after prior treatment.
  • You have tried a BTK inhibitor (a type of targeted therapy) before, either stopped it because it stopped working, your cancer got worse, or you had side effects.
  • You can be up and about for at least half the day (ECOG status 0 to 2).
  • You do not have cancer in your brain or spinal cord.
  • You have not had another cancer in the past 2 years, except for some early-stage cancers that were cured.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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