Test drug after early HER2-positive breast cancer surgery
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests zanidatamab, a type of targeted antibody treatment, in people with early-stage HER2-positive breast cancer to see how well it works and how safe it is. Because it’s a single-arm pilot study, everyone in the study gets the drug, and you’ll likely be asked to undergo standard surgery if appropriate.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re an adult (over 18) and can sign informed consent
- Your cancer is early-stage HER2-positive breast cancer with no spread to lymph nodes or distant organs
- Your tumor is larger than 1 cm but not bigger than 3 cm based on scans
- Your heart test (echocardiogram or MUGA) is within normal limits
- Blood tests and organ function are strong enough (enough blood cells, liver/kidney function within limits)
- You can (and will) use effective birth control, or you’re not able to have children
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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