Albumin treatment for advanced cirrhosis with fluid buildup
Treatments studied
Part of Digestive system clinical trials.
This trial tests whether a personalized long-term albumin (a blood protein medicine) can help people with advanced liver scarring who have fluid in the belly (ascites). It compares the personalized albumin approach to standard care to see if it improves outcomes over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older.
- You have advanced cirrhosis with signs of “worsening” that includes a Child-Pugh score between 7 and 12.
- You have ascites (fluid in the belly), confirmed by exam and/or ultrasound.
- At least 5 days have passed since your last liver worsening event or hospitalization.
- You cannot have certain conditions that would make albumin unsafe or make the trial less applicable (for example: very severe liver failure not caused by cirrhosis, or a recent TIPS procedure).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if taking branched-chain amino acids by mouth can help people with cirrhosis and ascites (fluid in the belly). It aims to improve nutrition and reduce complications.
This Phase 2 trial tests whether high-dose albumin can reduce “refractory ascites,” which is fluid buildup in the belly that doesn’t improve with the highest tolerated water pills (diuretics). If you have liver cirrhosis and need frequent drainage, this study may offer a new treatment option.
This Phase 2 trial tests whether giving albumin together with enoxaparin (a blood thinner) can improve outcomes for people hospitalized with decompensated cirrhosis who are at high risk. It may help your recovery after certain serious liver-related complications and reduce the chance of poor outcomes.
This study tests whether giving albumin (a protein) along with water pills helps reduce leg swelling in people with cirrhosis and ascites. It may be an option if your leg swelling hasn't improved with standard diuretics alone.
This trial tests whether giving albumin (a blood protein) in a personalized dose works better than a standard fixed dose for people with cirrhosis and sepsis-related acute kidney injury. The goal is to find a safer and more effective way to protect kidney function.
This trial tests whether giving human albumin through a vein can help people with liver cirrhosis who have confusion or drowsiness from a condition called hepatic encephalopathy. It is for patients with low albumin levels.
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