Clinical trials
Decompensated Cirrhosis and Ascites clinical trials
Below are recruiting decompensated cirrhosis and ascites clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06121479Enrolling by invitationPhase 3
Testing oral amino acid supplements for advanced liver disease
This trial tests if taking branched-chain amino acids by mouth can help people with cirrhosis and ascites (fluid in the belly). It aims to improve nutrition and reduce complications.
Bangkok, BangkokAges 18–85 - NCT05056220RecruitingPhase 3
Albumin treatment for advanced cirrhosis with fluid buildup
This trial tests whether a personalized long-term albumin (a blood protein medicine) can help people with advanced liver scarring who have fluid in the belly (ascites). It compares the personalized albumin approach to standard care to see if it improves outcomes over time.
LeuvenAges 18 years+ - NCT06533852RecruitingPhase 3
Fecal transplant trial for liver cirrhosis complications
This study tests whether stool from healthy donors can help people with advanced liver disease (cirrhosis) who have had complications like fluid buildup. You would receive the transplant through a colonoscopy or enema.
BarcelonaAges 18 years+ - NCT06764966RecruitingPhase 2
Statin and beta blocker study for liver disease
This trial tests if adding a statin to beta blocker treatment helps people with advanced liver disease (cirrhosis) who have had complications like fluid buildup, confusion, or bleeding. It is for patients who are already taking a non-selective beta blocker and will be followed for 12 months.
Charleston, West VirginiaAges 18 years+ - NCT06855056Recruiting
Studying new markers for recovery from liver cirrhosis complications
This study looks at new blood markers to better predict recovery in patients hospitalized for complications of cirrhosis (like fluid buildup, confusion, or bleeding). You may qualify if you were recently hospitalized for these issues and are expected to go home soon.
Clichy, FranceAges 18–80 - NCT03905746Recruiting
Study tests microRNA markers in worsened liver cirrhosis
This study looks at microRNA (tiny molecules in blood) to better understand what’s happening during sudden worsening of cirrhosis. It may help doctors recognize and monitor decompensated cirrhosis more accurately.
LyonAges 18 years+ - NCT07172035Recruiting
TIPS and liver recovery in decompensated cirrhosis
This trial studies whether a procedure called TIPS (a stent placed in the liver to improve blood flow) can help people with advanced liver disease regain better liver function. It is for patients who have had complications like severe bleeding from the stomach or difficult-to-control fluid buildup (ascites).
ChangshaAges 18–80 - NCT06812390RecruitingPhase 2
Albumin plus diuretics for cirrhosis-related leg swelling
This study tests whether giving albumin (a protein) along with water pills helps reduce leg swelling in people with cirrhosis and ascites. It may be an option if your leg swelling hasn't improved with standard diuretics alone.
West Haven, ConnecticutAges 18 years+ - NCT07002827Recruiting
Growth factors for early decompensated cirrhosis
This study tests whether a combination of two medicines (G-CSF and darbepoetin) given in one or more cycles can improve the body's immune and metabolic health in people with early-stage decompensated cirrhosis (advanced liver disease with mild complications). It compares these treatments with standard medical care.
New Delhi, National Capital Territory of DelhiAges 18–70 - NCT06576934Recruiting
Early TIPS for liver cirrhosis with ascites
This study tests whether placing a small tube (called a TIPS) early in the liver can help people with cirrhosis who have their first episode of moderate to severe belly fluid buildup. The goal is to see if this early procedure improves outcomes compared to standard care.
Freiburg im BreisgauAges 18–80 - NCT05895136RecruitingPhase 2
Albumin plus blood thinner for severe cirrhosis after hospital recovery
This Phase 2 trial tests whether giving albumin together with enoxaparin (a blood thinner) can improve outcomes for people hospitalized with decompensated cirrhosis who are at high risk. It may help your recovery after certain serious liver-related complications and reduce the chance of poor outcomes.
ClichyAges 18–80 - NCT05224960RecruitingPhase 2
Stem cell treatment for worsening liver cirrhosis
This trial tests umbilical-cord stem cells to see if they can improve outcomes in people with decompensated (worsening) cirrhosis. You may be considered if your liver disease is moderate to severe (MELD 15–30) and you do not have certain high-risk problems right now.
Lanzhou, GansuAges 18–75 - NCT07488546Enrolling by invitationPhase 1/Phase 2
HCL001 cell therapy for advanced liver cirrhosis
This trial tests a new cell injection called HCL001 for people with decompensated cirrhosis (advanced liver scarring causing complications). The goal is to see if it's safe and helps improve liver function. It may be an option if you've tried standard treatments and meet specific health criteria.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06223893Recruiting
Smartphone app to improve care after cirrhosis hospitalization
This study tests how well a smartphone app helps people with cirrhosis who have been hospitalized for sudden liver problems. It aims to improve care and access to treatment after you go home.
BirminghamAges 18 years+ - NCT06039696Recruiting
Testing a new way to find infections in liver disease patients
This trial uses a DNA test to better detect infections in people with advanced liver disease who are hospitalized. It may help doctors find the right treatment faster.
Guangzhou, GuangdongAges 18–80 - NCT04835480RecruitingPhase 2
Study drug for swelling from advanced liver scarring
This Phase 2 trial tests OsrHSA in people with advanced cirrhosis who have swollen belly fluid (ascites). It aims to see whether the treatment can improve outcomes in this difficult liver condition.
Changchun, JilinAges 18–80 - NCT04767945Recruiting
Cirrhosis patient hospital registry
This study keeps a record of people who have liver cirrhosis and were admitted to the hospital after a worsening event. It may help doctors better understand what leads to hospital stays and improve future care.
Banská BystricaAges 19 years+ - NCT07521332RecruitingPhase 4
Testing Apixaban to Prevent Bleeding Complications in Cirrhosis
This study tests whether a blood thinner called apixaban can safely prevent dangerous bleeding in people with cirrhosis (liver scarring) who have portal hypertension (high blood pressure in veins leading to the liver). The goal is to see if it reduces bleeding risk without causing excessive bleeding.
Hyderābād, SindhAges 18 years+ - NCT03826433RecruitingPhase 1
Study stem cell treatment for worsening hepatitis B cirrhosis
This Phase 1 study tests a stem cell product to see if it is safe and how it affects people with worsening hepatitis B-related cirrhosis. It may help researchers understand whether the treatment could improve liver function in this stage of illness.
Changsha, HunanAges 18–60 - NCT06741904Enrolling by invitation
Predicting liver disease worsening without invasive tests
This study looks at new, non-invasive methods to predict when chronic liver disease might get worse. It could help you and your doctor catch problems early without needing a biopsy or other invasive procedures.
Guangzhou, GuangzhouAges 18–80
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Common questions
- Are there clinical trials for decompensated cirrhosis and ascites?
- Yes. Clin2 currently lists 20 recruiting decompensated cirrhosis and ascites studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a decompensated cirrhosis and ascites trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a decompensated cirrhosis and ascites trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.