Tocilizumab for generalized myasthenia gravis symptoms
Part of Brain & nervous system, Cancer, Immune system & allergy clinical trials.
This trial tests whether tocilizumab can improve symptoms and safety in people with generalized myasthenia gravis (MG) who already take standard MG treatments. It may help if your weakness is still significant despite current therapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have MG confirmed by a positive anti-AChR antibody blood test
- Your MG is classified as Class II, III, or IV (more than mild eye-only symptoms)
- Your symptoms are fairly active on symptom scales at screening and at the start of the study
- Your muscle strength score is 11 or higher at screening
- You are already on stable MG medicines (no dose increases in the last 4 weeks for steroids or anti-cholinesterase, or stable non-steroid immune medicines for months)
- You do not have certain recent treatments or infections that could make this medicine unsafe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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