Fecal transplant and fiber for gut graft-versus-host disease
Treatments studied
Part of Blood & lymphatic, Digestive system clinical trials.
This study tests whether a fecal microbiota transplant (a procedure that puts healthy donor bacteria into your gut) combined with a dietary fiber supplement can help treat gut graft-versus-host disease, a common complication after a stem cell transplant. It may help reduce diarrhea and other gut symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a stem cell transplant within the last year.
- You have mild to severe gut graft-versus-host disease, confirmed by symptoms or biopsy.
- You are able to take the fecal transplant by mouth or through a colonoscopy.
- You are willing to collect stool samples and complete surveys.
- You are not pregnant or planning to become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether a fecal transplant (FMT) can help treat gut graft-versus-host disease (gut GVHD), a condition where donated immune cells attack the intestines. If you have gut GVHD and meet age requirements, you may be eligible to receive this treatment in the trial.
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This trial tests whether giving a fecal transplant (a procedure that transfers healthy bacteria from a donor's stool into your gut) can help children whose gut graft-versus-host disease (a common complication after a stem cell transplant) is not improving with standard steroid treatment.
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This study tests whether transplanting healthy donor stool into the gut can help children and young adults with ongoing digestive issues after a stem cell transplant. It may improve symptoms like diarrhea or the need for feeding tubes.
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