Clin2
NCT05078814Possibly a fitRecruiting

Survey of a heart and leg condition’s gene differences

Peripheral Artery Occlusive DiseaseAcute Coronary Syndrome

Part of Heart & circulation clinical trials.

This study collects information to understand how often certain genetic variants (ALDH gene family) show up in people with blocked leg arteries or an acute heart condition. The results may help researchers better understand the biology behind these illnesses.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
600 people
Ages
20 years and older
Study type
Observational

Who can take part

  • Be at least 20 years old
  • Have been diagnosed with blocked leg arteries (PAOD) using a test like ankle-brachial index, scan/angiography, ultrasound, CT, or a specialist’s exam
  • Have symptoms of leg pain when walking (claudication)
  • Also have a diagnosis of acute coronary syndrome (an urgent heart problem)
  • Be willing to participate—if you refuse, you cannot join

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04903912Recruiting
Study of people with blocked blood vessels or aneurysms

This registry study follows people with peripheral artery disease (blocked leg arteries), certain carotid artery narrowing, or an abdominal aortic aneurysm. It may help doctors better understand these conditions and improve care over time.

Naples
NCT02748226Recruiting
Study of artery procedures for leg artery disease outcomes

This study looks at results of a minimally invasive procedure done inside blood vessels (endovascular therapy) for people with painful or worsening leg artery disease. It uses both past (retrospective) and future (prospective) patient information to better understand outcomes.

Seoul
NCT07312383Recruiting
Skin blood flow study in leg artery disease

This trial uses a special device to measure tiny blood vessels in the skin of patients with severe leg artery disease. It aims to understand how blood flow changes before and after a common treatment to open blocked leg arteries (angioplasty).

Oslo
NCT07588295Recruiting
How immune cells respond in heart and leg blood vessel disease

This study examines how immune cells (macrophages) behave differently in patients with blocked arteries in the heart or legs. Understanding this may help doctors develop better treatments for these conditions.

Cotignola, Ravenna
NCT06223217Recruiting
New quality-of-life survey for leg artery disease patients

This study tests a new questionnaire (modified VascuQol) to measure how leg artery disease affects your daily life. It aims to create a better tool for doctors to track your symptoms and well-being.

Shanghai, Shanghai Municipality
NCT06758921Recruiting
Testing a catheter for leg artery blockages

This study tests a special catheter to open blocked arteries in the thigh, knee, or lower leg. It may help improve blood flow and reduce symptoms like leg pain or wounds.

Graz

Hear when a new Peripheral Artery Occlusive Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.