How immune cells respond in heart and leg blood vessel disease
Part of Heart & circulation clinical trials.
This study examines how immune cells (macrophages) behave differently in patients with blocked arteries in the heart or legs. Understanding this may help doctors develop better treatments for these conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have chronic coronary artery disease (blocked heart arteries that develop slowly) OR a heart attack without ST elevation OR leg pain from poor circulation OR severe leg ischemia (very poor blood flow to the legs)
- Your kidneys are working adequately (not in severe failure)
- You do not have severe heart valve disease or advanced heart failure
- Your liver is functioning reasonably well (not advanced disease)
- You do not have a chronic autoimmune or inflammatory condition like rheumatoid arthritis or lupus
- You are not currently taking anti-inflammatory drugs (like certain corticosteroids) and do not have an active infection or recent surgery
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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