Testing a methyl-donor supplement to study lupus metabolism
Part of Hormones & metabolism clinical trials.
This study looks at whether a “methyl-donor” nutrient supplement changes metabolism (methylation) in people with lupus who are also in the childbearing age range and have low-to-moderate disease activity. It may help researchers understand why lupus acts differently in some people and how diet-related pathways could affect symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of systemic lupus (SLE).
- You are female, age 18 to 45, and have not reached menopause.
- Your lupus symptoms are currently low activity (SLEDAI-2K score 4 or less).
- You are taking prednisone less than 10 mg per day and have been on a stable dose of chloroquine.
- You must not be pregnant and must not be currently taking vitamin B12 and/or folic acid supplements.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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