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NCT05166070Possibly a fitRecruiting

RD133 for mesothelin-positive tumors after prior treatments

Solid Tumor

Part of Cancer clinical trials.

This early-phase study tests RD133, an experimental treatment, in adults whose solid tumors are mesothelin-positive and have come back or not responded to prior standard therapies. It aims to see how well RD133 can control these cancers and what side effects it causes.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
24 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Be 18 or older and sign an informed consent form before any study steps
  • Have already tried at least 2 standard treatments, and the last one did not work
  • Your tumor must test “mesothelin-positive” on the cancer cell surface in lab testing (over 25% of tumor cells)
  • Have scans showing at least one measurable tumor spot that can be followed, and expect to live at least 12 weeks
  • Have enough blood counts and organ function based on lab tests (neutrophils, platelets, hemoglobin, liver and kidney tests)
  • Have heart ultrasound showing adequate pumping (ejection fraction ≥ 50%) and enough oxygen levels; also meet basic clotting test ranges

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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