Clin2
NCT05173233Possibly a fitNot yet recruiting

Clip procedure to repair leaking tricuspid valve

Tricuspid Regurgitation

Part of Heart & circulation clinical trials.

This trial studies whether a heart procedure called K-Clip TM helps people with severe “secondary” tricuspid valve leakage who are at high risk for open-heart surgery. It aims to improve symptoms and valve function using a less-invasive, catheter-based repair.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
67 people
Ages
60 years and older
Study type
Interventional

Who can take part

  • You are age 60 or older (man or woman).
  • You have severe or worse secondary tricuspid regurgitation (leaking), and you have symptoms like shortness of breath, leg swelling, or fluid in the belly.
  • Your heart strength is still reduced but not too low (left ventricle ejection fraction is 40% or higher).
  • You’ve had the best usual medicines for tricuspid leakage for at least 30 days and your symptoms have been stable.
  • Your valve leak causes limitations in daily life (NYHA heart-failure class 2 to 4).
  • A heart team agrees you are high risk for surgery and the clip procedure is expected to help, and you (or your guardian) sign informed consent.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05434507Recruiting
Clip procedure for leaking tricuspid valve in high-risk patients

This trial studies whether a minimally invasive “clip” procedure can safely improve tricuspid valve leakage (a heart valve that doesn’t close tightly). It focuses on older adults who are considered too high-risk for open-heart surgery and still have enough heart pumping strength to benefit.

Shanghai, Shanghai Municipality
NCT07133386Not yet recruiting
TriClip for Severe Tricuspid Regurgitation – UK Study

This study tests a device called TriClip to repair a leaky tricuspid valve in the heart. If the leak is reduced, you may have less shortness of breath and feel more energetic.

London
NCT05179616Recruiting
Study of TriClip treatment for severe leaky tricuspid valve

This study follows adults with a severely leaky tricuspid heart valve who still have symptoms despite medication. It looks at outcomes after a procedure called TriClip, which helps reduce valve leakage.

Pforzheim
NCT07140562Recruiting
Catheter-based repair for severe tricuspid valve leak

This study tests a new catheter-based device to repair a leaky tricuspid heart valve (tricuspid regurgitation) in people who still have symptoms like shortness of breath or swelling despite taking heart medications. The goal is to see if the procedure is safe and can help reduce the leak.

Asunción
NCT06920745Recruiting
TriClip study for severe tricuspid regurgitation

This study is testing whether the TriClip device helps people with severe tricuspid regurgitation (a leaky heart valve) feel better. It compares people who received the TriClip to those who didn't get the procedure.

Santa Clara, California
NCT03692598Recruiting
Transcatheter repair for leaky tricuspid valve during heart surgery

This trial studies a catheter-based repair to help fix a leaky tricuspid valve (regurgitation), especially when you’re also having another heart surgery. It aims to improve valve function and symptoms while tracking safety and outcomes.

Aarhus

Hear when a new Tricuspid Regurgitation trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.