Tricuspid valve leak study
Part of Heart & circulation clinical trials.
This trial tests a procedure that uses a small clip to fix a leaky tricuspid valve in the heart. The goal is to reduce symptoms like shortness of breath and fatigue, and help you feel better in your daily life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older and have severe or more symptomatic tricuspid regurgitation (a leaky heart valve on the right side).
- You need to be on the best possible heart medications (including water pills) for at least 30 days, with no changes in the last month.
- Your symptoms should limit your daily activities—your doctor will use a questionnaire (KCCQ) to check this.
- The doctor must see that your valve shape is suitable for a clip procedure (TEER) that can reduce the leak to moderate or less.
- You must be able to give written informed consent and follow the study plan.
- You cannot have certain other conditions, like severe blockage in other heart valves, recent stroke, bleeding problems, or ongoing infections.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study follows adults with a severely leaky tricuspid heart valve who still have symptoms despite medication. It looks at outcomes after a procedure called TriClip, which helps reduce valve leakage.
This study tests a clip device to fix a leaky tricuspid valve without open-heart surgery. It may help people who have symptoms like breathlessness or swelling and are not good candidates for surgery.
This study tests a new catheter-based device to repair a leaky tricuspid heart valve (tricuspid regurgitation) in people who still have symptoms like shortness of breath or swelling despite taking heart medications. The goal is to see if the procedure is safe and can help reduce the leak.
This study tests if a less invasive tricuspid valve repair or replacement can protect kidney function and improve physical activity in older adults with severe tricuspid valve leakage.
This trial tests a catheter-based procedure (done through the blood vessels) to repair a severely leaky tricuspid valve. It may help people with symptoms or past hospitalizations from tricuspid valve leakage who are higher-risk for standard surgery.
This trial tests the DragonFly-T system to improve symptoms and heart function in people with severe tricuspid regurgitation (a leaky heart valve) using a catheter-based repair. It may help reduce valve leak–related symptoms when standard medication isn’t enough and surgery risk is higher.
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