Albumin-bound chemo plus anti-blood-vessel drugs for TNBC
Treatments studied
Part of Cancer, Skin clinical trials.
This Phase 2 study tests a chemotherapy called albumin-bound paclitaxel combined with medicines that block new blood vessel growth (antiangiogenic agents) for women with recurrent or metastatic triple-negative breast cancer. It aims to see whether this combination can better control cancer when it comes back or has spread.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman age 18 to 80.
- You have triple-negative breast cancer that has returned or spread (confirmed by pathology and scans).
- Your scans show at least one measurable tumor area.
- You have not had chemotherapy for the advanced/recurrent stage; if you had chemo before, you must be at least 12 months past it (or 6 months past radiation).
- Your overall health is fairly good (ECOG performance status 0 to 2) and you’re expected to live at least 3 months.
- You meet certain blood and organ check results (for example, adequate blood counts, liver tests, and kidney function) and have safe clotting test results.
- You must not be pregnant or breastfeeding, and you must be able to take medicines reliably by mouth (no major swallowing problems or certain gut issues).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 3 trial compares an “anti-blood-vessel” drug added to chemotherapy versus chemotherapy alone for people with stage II–IIIC triple-negative breast cancer that has been completely removed with surgery. The goal is to see if adding the study drug improves outcomes after surgery (adjuvant treatment).
This trial tests whether using blood tests and imaging during chemotherapy and immunotherapy can help guide treatment for early-stage triple-negative breast cancer. It aims to improve outcomes by adjusting treatment based on how the cancer responds.
This trial studies giving camrelizumab plus apatinib and chemotherapy before surgery for triple-negative breast cancer. The goal is to shrink the tumor and improve outcomes by testing a combination of immune and targeted medicines along with chemotherapy.
This Phase 2 trial tests a treatment for people with triple-negative breast cancer that has come back or spread and has continued to progress despite earlier therapies. It may help by trying a new approach in patients who still have enough health to safely receive more treatment.
This trial tests a new drug called LBL-024, either alone or with other medicines, for people with triple negative breast cancer. It aims to see if the drug can shrink tumors and how safe it is.
This trial tests a new drug called SKB264 against standard chemotherapy options for people with advanced triple-negative breast cancer who have not yet received chemotherapy for their advanced disease. The goal is to see if SKB264 works better than the usual treatments.
Hear when a new Triple Negative Breast Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.