Study drug AB8939 for AML after prior treatments
Treatments studied
Part of Blood & lymphatic, Cancer, Genetic & congenital clinical trials.
This Phase 1/2 study tests AB8939 in people with acute myeloid leukemia (AML) whose disease has come back or did not respond to earlier treatment. It may help researchers find a safe dose and learn whether the treatment can control the leukemia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of acute myeloid leukemia (AML) based on the latest WHO criteria
- You are in the “second or third” round of treatment (meaning you’ve already had prior therapy)
- Your general health and strength are limited (ECOG score about 0–1 for the dose-escalation part, or 0–2 for the expansion part)
- You cannot be eligible for standard-of-care treatment at the time you join
- You should not be planning or eligible for a stem cell transplant (HSCT) now, and you must not have had one in the last 100 days
- You can have extra testing, including bone marrow biopsies, and you can sign the consent form and follow study visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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