IV esketamine to improve long-term pain in CRPS
Part of Brain & nervous system clinical trials.
This study looks at whether giving esketamine through a vein can help reduce long-term pain in people with complex regional pain syndrome (CRPS). You may be able to join if your CRPS diagnosis matches specific international criteria and you can safely take the study medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have CRPS that fits the IASP “Budapest” diagnosis rules (or CRPS with some features in remission)
- Your CRPS affects only one arm and/or only one leg
- You’re able and willing to take part in study activities
- You can understand Dutch well enough to participate
- You are 18 years old or older
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if esketamine, a nasal spray, can reduce chronic pelvic pain in women with endometriosis that hasn't improved with standard painkillers. You may qualify if you have severe pain and are scheduled for endometriosis surgery.
This trial compares two strong pain medicines—fentanyl and esketamine—to see which works better for treating pain right after a traumatic injury. You would receive the medicine by spray in your nose or through a vein before going to the hospital.
This trial tests if low-dose S-ketamine, given as a short intravenous infusion, can safely improve fibromyalgia pain and other symptoms for people who haven't gotten enough relief from non-drug treatments. S-ketamine is a fast-acting medicine that blocks pain signals and may help reset how the brain processes pain.
This Phase 1/2 study tests hydroxynorketamine (a related ketamine-type medicine) to see if it can reduce chronic nerve pain in the arms or legs. You may be able to join if you have nerve pain for more than 3 months and meet safety and health check requirements.
This trial is testing whether a combination of ketamine and talk therapy can help people with depression that hasn't responded to other treatments. You will receive ketamine in a safe, supervised setting while working with a therapist.
This trial tests if ketamine combined with talk therapy helps people with both chronic pain and PTSD. Participants receive ketamine through an IV in group therapy sessions over several weeks, with the goal of reducing pain and PTSD symptoms.
Hear when a new Complex Regional Pain Syndromes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.