Clinical trials
Complex Regional Pain Syndromes clinical trials
Below are recruiting complex regional pain syndromes clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07791966Recruiting
Brain stimulation for chronic pain
This study tests a non-invasive brain stimulation technique to help people with chronic pain, specifically Complex Regional Pain Syndrome (CRPS), manage pain-related avoidance behaviors. It may help reduce pain and improve daily function.
Cleveland, OhioAges 18 years+ - NCT07785362Enrolling by invitation
Brain stimulation for teens with fibromyalgia or chronic pain
This study tests a non-invasive brain stimulation technique to see if it can reduce pain in teenagers and young adults with fibromyalgia or other long-lasting muscle and bone pain that hasn't responded to usual treatments. It aims to help calm overactive pain signals in the brain.
Genova, GEAges 10–21 - NCT07446712Recruiting
Oxygen Therapy for Complex Regional Pain Syndrome
This trial tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help reduce pain from Complex Regional Pain Syndrome (CRPS) Type I. If you have this condition, the therapy may improve your symptoms.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT07777081Recruiting
How your brain and body recover after a wrist fracture
This study looks at how your brain and body heal after a wrist fracture. By joining, you'll help doctors understand recovery better, which could improve care for future patients.
Cambridge, CambridgeshireAges 18 years+ - NCT07210515RecruitingPhase 3
Testing Ambros Therapy for Early CRPS
This trial tests if an intravenous medicine called AMBTX-01 (neridronate) can help people with early-stage Complex Regional Pain Syndrome (CRPS) type 1. It focuses on those whose affected limb feels warm, looks red, and is swollen.
Phoenix, ArizonaAges 18 years+ - NCT07568015Recruiting
Nerve-targeted treatment for lateral hip pain
This study tests an experimental treatment that targets nerves around the hip to relieve pain on the outside of the hip. It may help people who have tried other treatments without enough relief.
Sun City, ArizonaAges 22–80 - NCT07744269Recruiting
Hand therapy for early complex regional pain syndrome
This trial compares two hand therapy techniques — contrast baths (alternating warm and cool water) and compression with whirlpool therapy — to see which better eases early-stage complex regional pain syndrome (CRPS) after a hand or wrist injury. If you've had hand or wrist trauma and are still in pain, this study might help you find a treatment that reduces discomfort and improves hand use.
Ankara, YenimahalleAges 18–80 - NCT03612193Recruiting
Study how gut bacteria relates to complex regional pain
This study looks at differences in gut bacteria (from a stool sample) in people with complex regional pain syndrome (CRPS) and in people who live with them. The goal is to understand whether gut microbes might play a role in CRPS and improve understanding of the condition.
St Louis, MissouriAges 18 years+ - NCT03838107Recruiting
Tracking changes in pediatric CRPS using study markers
This study looks at how signs in the body change over time in children with CRPS (complex regional pain syndrome). It mainly involves being assessed alongside the usual CRPS care, and often includes MRI checks to better understand the pain course.
Cincinnati, OhioAges 10–17 - NCT04144972Recruiting
Closed-loop deep brain stimulation for long-lasting nerve pain
This trial tests a “smart” deep brain stimulation device that senses your brain signals and adjusts treatment to reduce severe, long-lasting pain. It may help people whose pain has not improved with multiple pain medicines and surgery cannot fix the cause.
San Francisco, CaliforniaAges 22–80 - NCT04909138Recruiting
Intermittent nerve stimulation instead of daily low-frequency therapy
This study tests whether switching from continuous implanted nerve stimulation to an intermittent schedule can keep pain relief for people with chronic back and/or leg pain. You would be compared in a structured study plan to see if the alternate dosing works for you and is safe.
Chicago, IllinoisAges 18–90 - NCT05034835Recruiting
Compression garments for arm nerve pain in CRPS
This study tests whether wearing a special compression sleeve or garment can reduce pain in people with complex regional pain syndrome (CRPS) affecting the arm. It’s looking at pain changes while making sure it’s safe for your skin and blood flow.
Ploemeur, Brittany RegionAges 18 years+ - NCT05052736Recruiting
Noninvasive brain/nerve stimulation for early CRPS type I
This trial studies a noninvasive stimulation treatment to help people with early-stage complex regional pain syndrome (CRPS) type I. It may help calm nerve-related pain, especially soon after symptoms begin.
Las Palmas de Gran Canaria, Palmas, LasAges 18 years+ - NCT05689944Recruiting
Dance therapy for teens with chronic pain
This trial studies whether dance therapy can help reduce chronic pain in teens when usual pain treatments haven’t worked well. It may be helpful if you’re followed in a pain clinic and are able to participate in movement-based sessions.
BronAges 12–20 - NCT05777889Recruiting
Infrared imaging for nerve-stimulation pain in one leg
This study uses infrared images to help evaluate spinal cord stimulation for complex regional pain syndrome (CRPS) when it affects one leg. It aims to see whether the imaging approach matches pain and treatment needs in people whose pain hasn’t improved with standard care.
New York, New YorkAges 18–85 - NCT05814497Recruiting
Brain scan study of how kids process chronic pain
This study looks at how the brain processes pain sensations in children with certain long-lasting pain conditions. It may help researchers understand what’s happening in the nervous system and guide better treatments.
Cincinnati, OhioAges 10–17 - NCT06393101RecruitingPhase 1
High-CBD cannabis extract for complex regional pain syndrome treatment
This study tests a high-CBD cannabis extract (BRC-002) to see if it can help reduce pain and improve health in people with Complex Regional Pain Syndrome (CRPS). Participants will not use opioids or other cannabis during the study.
La Jolla, CaliforniaAges 21–75 - NCT06421350Recruiting
Closed-loop spinal cord stimulation for complex regional pain syndrome
This trial tests a new type of spinal cord stimulator that automatically adjusts to your pain signals. It may help people with complex regional pain syndrome (CRPS) who have not tried this kind of therapy before.
La Jolla, CaliforniaAges 18 years+ - NCT06453447Recruiting
Prednisone to prevent CRPS after wrist fracture surgery
This trial tests whether a short course of the steroid prednisone can prevent or reduce complex regional pain syndrome (CRPS) after wrist surgery. It is for people who had a broken wrist fixed with a plate and screws and have a higher chance of developing CRPS.
Vancouver, British ColumbiaAges 19 years+ - NCT06769373Recruiting
Whirlpool and contrast bath for CRPS after wrist fracture
This study tests whether warm water whirlpool baths or alternating hot and cold water baths (contrast bath) can help reduce pain and improve function in people with Complex Regional Pain Syndrome (CRPS) after a wrist fracture that was treated without surgery.
Afyonkarahisar, AfyonkarahisarAges 18–70 - NCT06835868Recruiting
Registry for nerve stimulation treatments for chronic pain in Belgium
This trial creates a registry for people with chronic pain who are getting special nerve-modulating treatments in Belgium. It focuses on two specific chronic pain conditions: Persistent Spinal Pain Syndrome Type 2 (pain after spine surgery) and Complex Regional Pain Syndrome (a type of nerve pain).
Edegem, AntwerpAges Any age - NCT07129811Recruiting
Nerve block for chronic pain syndrome
This trial tests a nerve block injection (stellate ganglion block) to treat complex regional pain syndrome, a chronic pain condition. It may help if your pain is severe and other treatments haven't worked.
Ankara, ÇankayaAges 18–75 - NCT07208825Recruiting
Conservative care for complex regional pain syndrome
This study tests whether a conservative treatment plan can help people with complex regional pain syndrome (CRPS), a condition where pain lasts longer than expected after an injury. You may qualify if you have had CRPS symptoms for up to 5 years and are between ages 18 and 70.
Oulu, North OstrobothniaAges 18–70 - NCT07349173Recruiting
Testing a new way to assess hand and arm awareness
This study explores how people perceive the space around their affected arm or hand after a condition called 'exclusion' (partial loss of awareness or use). It uses virtual reality to test this, which might lead to better therapies.
NancyAges 18 years+
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Complex Regional Pain Syndromes trials by city
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Complex Regional Pain Syndromes trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for complex regional pain syndromes?
- Yes. Clin2 currently lists 33 recruiting complex regional pain syndromes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a complex regional pain syndromes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a complex regional pain syndromes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.