Vaginal estrogen vs oral bladder medicine for overactive bladder
Treatments studied
Part of Kidney & urinary clinical trials.
This study compares vaginal estradiol (a hormone placed in the vagina) versus an oral beta-3 medicine called mirabegron for overactive bladder symptoms. It looks to see which treatment works better and is safer for postmenopausal women.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have overactive bladder symptoms that score high on a specific questionnaire (OAB-q SF).
- You are postmenopausal (for example, no period for 12 months or certain past uterus/ovary situations).
- You can read and speak English well enough to take study questionnaires.
- You do not have reasons you can’t take vaginal estrogen or mirabegron.
- Your bladder is emptying well (post-void leftover urine is not too high).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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