Clinical trials
Overactive Bladder Syndrome clinical trials
Below are recruiting overactive bladder syndrome clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07553065RecruitingPhase 2
Bladder Treatment Study with NT 201 and Vibe System
This study tests a new bladder treatment called NT 201 combined with a device called the Vibe System for women with overactive bladder (frequent, urgent need to urinate). The treatment is injected directly into the bladder and may help reduce urgency and leaking.
Reno, NevadaAges 18–80 - NCT05221021RecruitingPhase 4
Vaginal estrogen vs oral bladder medicine for overactive bladder
This study compares vaginal estradiol (a hormone placed in the vagina) versus an oral beta-3 medicine called mirabegron for overactive bladder symptoms. It looks to see which treatment works better and is safer for postmenopausal women.
Bethesda, MarylandAges 18 years+ - NCT06546189Recruiting
Probiotics for overactive bladder treatment
This study tests whether a daily probiotic supplement (Lactobacillus) can help reduce overactive bladder symptoms. It compares the supplement to a placebo in a randomized trial.
ViennaAges 18 years+ - NCT06283498Enrolling by invitation
Radiofrequency treatment for overactive bladder
This study tests a new non-surgical treatment for overactive bladder using radiofrequency energy delivered through the vagina to calm the nerves that cause urgency and leaking. It is for people who have urge incontinence and have not found relief from medication.
Corona del Mar, CaliforniaAges 21–80 - NCT06094543Recruiting
Improving access and adherence for overactive bladder treatment
This study compares two ways to help women with overactive bladder get treatment and stick with it. You might be able to join if you are a woman with ongoing OAB symptoms and haven't had certain treatments recently.
Redwood City, CaliforniaAges 18 years+ - NCT03952299RecruitingPhase 3
Oxybutynin patch after bladder surgery for children’s urgency pain
This study tests whether an oxybutynin skin patch after bladder surgery can reduce bladder pain and urgent, frequent urination in children. It compares symptoms after surgery to see if the patch helps more than the control plan.
Sacramento, CaliforniaAges 4–8 - NCT04020510RecruitingPhase 4
Standard versus fewer bladder Botox injections for overactive bladder
This study compares the usual amount of Botox injected into the bladder versus a smaller amount. It aims to see whether fewer injections can reduce overactive bladder symptoms with fewer side effects, like trouble emptying the bladder.
Bethesda, MarylandAges 18 years+ - NCT04873037Recruiting
BTL Emsella chair vs sham for overactive bladder relief
This trial tests whether a specialized chair treatment (BTL Emsella) can reduce bladder urgency and overactive bladder symptoms compared with a sham (placebo) chair session. It may help people who have already tried behavioral steps and/or bladder medications but still have symptoms.
Royal Oak, MichiganAges 18 years+ - NCT05878951RecruitingPhase 2/Phase 3
Botox during HoLEP for men with overactive bladder symptoms
This study tests whether adding a Botox shot into the bladder during HoLEP surgery helps men with overactive bladder symptoms like urgency, frequent urination, and accidents. You’d be compared to the standard approach to see if symptoms improve after surgery.
Chicago, IllinoisAges 18–89 - NCT06201013Recruiting
Vitamin D for children with wet overactive bladder
This trial tests whether giving vitamin D to children with 'wet' overactive bladder (OAB) – where they leak urine with sudden urges – can help improve symptoms. It's for children aged 5 and older who have low vitamin D levels and no other serious health conditions.
Chongqing, Chongqing MunicipalityAges 5–18 - NCT06387329RecruitingPhase 4
Antibiotic to prevent UTI after bladder Botox
This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.
Bethesda, MarylandAges 18 years+ - NCT07081412Recruiting
Home-based nerve stimulation for overactive bladder
This trial tests if a nerve stimulation treatment, usually done in a clinic, can be done at home using a mobile app. It aims to help women with overactive bladder symptoms like sudden urges to urinate.
Izmir, İzmirAges 18 years+ - NCT07184307Recruiting
Platelet-rich plasma vs botox for stubborn overactive bladder
This trial compares two treatments for overactive bladder (OAB) that hasn't improved with standard medications: injections of platelet-rich plasma (a substance from your own blood) versus botulinum toxin (Botox). Both are injected into the bladder to help reduce urgency and leakage.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07209397Recruiting
Radiofrequency treatment for overactive bladder in women
This trial tests a new procedure that uses radiofrequency energy to calm the nerve responsible for overactive bladder in women. It aims to reduce urge-related urine leaks without surgery or medications.
Palo Alto, CaliforniaAges 22–80 - NCT07416968RecruitingPhase 4
Low dose tadalafil vs solifenacin for overactive bladder in women
This study compares two medications—tadalafil (a daily pill for blood flow) and solifenacin (a pill that relaxes the bladder)—to see which works better for women with overactive bladder (OAB), which causes sudden, strong urges to urinate. It will help doctors find a treatment that may have fewer side effects.
Shibīn al Kawm, Al-MinūfiyyahAges 18–75 - NCT07563764Recruiting
Shock Wave Therapy for Overactive Bladder in Women
This study tests whether low-energy shock wave therapy can reduce frequent urination, nighttime bathroom trips, and sudden urges to urinate in women who also have metabolic syndrome (a combination of conditions like high blood pressure, high blood sugar, and extra belly fat). The therapy is non-invasive and may offer an alternative to medications or injections.
Kaohsiung, TaiwanAges 20–75 - NCT06780657Enrolling by invitation
Hypopressive exercises for overactive bladder syndrome
This trial tests a gentle exercise method (hypopressive exercises) for people with overactive bladder. The exercises involve special breathing and posture techniques to help strengthen the pelvic floor without putting strain on the body.
Denizli, DenizliAges 18–65 - NCT06212661Enrolling by invitation
Study on migraine drugs and bladder symptoms
This study looks at how certain migraine treatments affect bladder symptoms like frequent or urgent urination. If you have hard-to-treat migraines and are starting a CGRP inhibitor or Botox injections, you may be able to join.
Cleveland, OhioAges 18 years+ - NCT07494864Recruiting
Urinary tract health and microbiome study
This study looks at how bacteria and the immune system affect the lower urinary tract. It includes healthy volunteers and people with various urinary conditions, like infections or bladder pain.
Zurich, Canton of ZurichAges 18 years+ - NCT06341673Recruiting
Nerve stimulation for bladder symptoms in multiple sclerosis
This trial tests a nerve stimulation treatment (TTNS) to improve bladder symptoms like urgency or frequent urination in people with multiple sclerosis. It is a randomized controlled study comparing this approach to a control, and aims to see if it can reduce bothersome bladder issues.
Khobar, Eastern ProvidenceAges 18 years+ - NCT06226220Recruiting
Nerve test for bladder device success in women
This study tests how well a short, in-office nerve evaluation (PNE) predicts the success of sacral neuromodulation—a treatment that uses mild electrical pulses to calm bladder nerves. It is for women with urgency leaking or very frequent urination.
Chicago, IllinoisAges 18 years+ - NCT07171424Enrolling by invitation
Understanding symptom questionnaires for overactive bladder
This study aims to better understand symptom questionnaires for women with overactive bladder (OAB). It will help doctors and patients know what changes in symptom scores mean for daily life.
IstanbulAges 18 years+ - NCT07025044Recruiting
Bladder microbiome study for women with overactive bladder getting Botox
This study looks at the bacteria in the bladders of women with overactive bladder who are getting Botox injections. It aims to understand how these bacteria might affect treatment results.
Washington D.C., District of ColumbiaAges 55 years+ - NCT04527445Recruiting
Test to use less X-ray during sacral nerve lead placement
This trial studies whether doctors can place a sacral neuromodulation lead using fewer X-rays. If you’re getting this procedure for overactive bladder, it may help reduce radiation exposure while still guiding correct lead placement.
Loma Linda, CaliforniaAges 18–89
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Overactive Bladder Syndrome trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for overactive bladder syndrome?
- Yes. Clin2 currently lists 30 recruiting overactive bladder syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overactive bladder syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overactive bladder syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.