Clin2
NCT05226247Possibly a fitRecruiting

Check whether careful weaning prevents lung fluid buildup

Mechanical Ventilation ComplicationPulmonary Edema

Part of Lungs & breathing clinical trials.

This study looks at people on a breathing machine for more than 48 hours who are starting a “spontaneous breathing trial,” a test used to see if they can breathe on their own. It focuses on those at higher risk of “weaning-induced pulmonary edema,” meaning fluid can collect in the lungs during the weaning process.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
250 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You’re 18 or older (and not pregnant).
  • You’ve been on an invasive breathing machine for more than 48 hours.
  • Your ICU team is planning a spontaneous breathing trial based on oxygen and ventilator settings, plus cough and alertness checks.
  • You have at least one higher-risk condition for lung fluid during weaning: obesity, chronic COPD, or chronic heart disease.
  • You do not have any major exclusions like DNR (no resuscitation plan), tracheostomy, pacemaker, or severe heart valve disease.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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