Clin2
NCT05231798Possibly a fitRecruiting

PET and brain scans in adults with Down syndrome

Down SyndromeDown Syndrome, Partial Trisomy 21Alzheimer Disease

Part of Brain & nervous system, Genetic & congenital, Mental health clinical trials.

This study looks at how well a brain chemical system works in adults with Down syndrome as they age, including how it relates to Alzheimer’s-type brain changes and thinking skills. It uses brain scans and memory/thinking tests to see whether these measures can help track risk or changes over time.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years to 55 years
Study type
Interventional

Who can take part

  • You have Down syndrome (including mosaic or partial trisomy 21)
  • You’re between 18 and 55 years old, and you do not currently have dementia
  • You can take part for the full study, including brain scans and thinking tests
  • Your vision and hearing are good enough to complete the thinking tests
  • If you take brain/cancer/nerve medicines that affect the brain, your dose must be stable for about 4 weeks (or the team reviews timing)
  • A reliable study partner (caregiver or family member) can share your history and symptoms

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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