Clin2
NCT05270096Possibly a fitRecruiting

Matches children and young people to leukemia treatment plans

Relapsed Hematologic MalignancyRefractory Hematologic Malignancy

Part of Blood & lymphatic, Cancer clinical trials.

This trial is set up to review tumor lab test results to help doctors choose the most appropriate next treatment for people with leukemia that has returned or did not respond. It mainly matters for younger patients who are not already on a standard treatment path.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
600 people
Ages
birth to 25 years
Study type
Observational

Who can take part

  • You (or your child) have leukemia or another blood cancer that is back or not responding
  • You were diagnosed before age 18, and you are under 25 when you join the study
  • You are being treated in a pediatric or young adult (AYA) cancer program, with no current standard treatment plan
  • Your expected lifetime is at least 6 weeks
  • Your tumor has had molecular testing, and the results are available
  • Your tumor has had flow cytometry testing in a certified lab, and the results are available

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04307576Recruiting· Phase 3
Study for newly diagnosed ALL children and young adults

This Phase 3 trial studies a treatment plan for people up to age 45 who are newly diagnosed with B-cell or T-cell acute lymphoblastic leukemia (ALL). The goal is to see whether the study treatment improves outcomes compared with standard approaches.

Brussels
NCT05994690Recruiting· Phase 3
Newly diagnosed pediatric AML trial with extra treatment options

This trial studies different treatment plans for children and teens newly diagnosed with AML (a type of blood cancer). Depending on the child's tumor markers and risk group, they may be offered an extra drug (quizartinib) or a targeted antibody (Mylotarg) to see if it improves outcomes.

Utrecht, Utrecht
NCT06233526Recruiting
Personalized treatment for children with relapsed or resistant AML

This trial offers a personalized treatment plan for children with hard-to-treat or relapsed acute myeloid leukemia (AML). The plan is based on the unique genetic makeup of the child's cancer and lab tests that find the most effective drugs.

Hangzhou, Zhejiang
NCT03643276Recruiting· Phase 3
Study of treatment plans for children with leukemia

This Phase 3 trial tests a specific treatment protocol for children and teens newly diagnosed with certain types of leukemia, aiming to improve outcomes while managing side effects. You may be invited if your child’s leukemia type and timing fit the study rules.

Sydney
NCT05745714Recruiting· Phase 1/Phase 2
Targeted triple-combination treatment for children with relapsed blood cancers

This Phase 1/2 study tests a multi-drug combination (ruxolitinib, venetoclax, dexamethasone, plus chemotherapy) for children whose blood cancer has come back or did not respond. It aims to reduce the cancer by targeting specific genetic changes and may offer a new option when standard treatments have not worked.

Vienna
NCT06347458Not yet recruiting· Phase 1
Cell therapy for children with returning or hard-to-treat AML

This trial tests a new cell therapy (BG1805) for children whose acute myeloid leukemia (AML) has returned or not responded to standard treatment. The therapy targets a specific marker on leukemia cells called CLL-1 and aims to help the immune system fight the cancer.

Hear when a new Relapsed Hematologic Malignancy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.