Clin2
NCT03643276Possibly a fitRecruiting

Study of treatment plans for children with leukemia

Acute Lymphoblastic Leukemia, Pediatric

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This Phase 3 trial tests a specific treatment protocol for children and teens newly diagnosed with certain types of leukemia, aiming to improve outcomes while managing side effects. You may be invited if your child’s leukemia type and timing fit the study rules.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
5,000 people
Ages
Up to 17 years
Study type
Interventional

Who can take part

  • Your child is under 18 years old at diagnosis (up to 17 years and 365 days)
  • Your child has newly diagnosed acute lymphoblastic leukemia, or a specific mixed-type leukemia that can be treated like ALL
  • Your child is being treated at a participating study center
  • Your family can sign consent for the trial and for sharing/processing the trial data
  • The leukemia is not the Ph+ type (BCR-ABL1 or t(9;22) positive)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04307576Recruiting· Phase 3
Study for newly diagnosed ALL children and young adults

This Phase 3 trial studies a treatment plan for people up to age 45 who are newly diagnosed with B-cell or T-cell acute lymphoblastic leukemia (ALL). The goal is to see whether the study treatment improves outcomes compared with standard approaches.

Brussels
NCT06764238Recruiting· Phase 2/Phase 3
Treatment study for children with new B-cell ALL (intermediate/high risk)

This trial tests a treatment plan for children and teens newly diagnosed with B-cell acute lymphoblastic leukemia (ALL) that is intermediate or high risk. The goal is to find the best way to treat the cancer and improve outcomes.

Hefei, Anhui
NCT07443592Not yet recruiting
Treatment for adults up to 65 with newly diagnosed ALL

This trial tests a treatment plan for adults aged 18 to 65 who have just been diagnosed with a type of acute lymphoblastic leukemia (ALL) that does not have the Philadelphia chromosome (Ph-negative). The goal is to see how well this therapy works and how safe it is.

A Coruña
NCT06124157Recruiting· Phase 2
Targeted therapy plus chemo for children with Ph+ or Ph-like B-ALL

This trial tests if adding a targeted drug (dasatinib or imatinib) to a chemotherapy combination with blinatumomab works better for children and young adults with a specific genetic form of B-cell acute lymphoblastic leukemia. The goal is to see if this approach can improve treatment outcomes for patients with Philadelphia chromosome-positive or ABL-class Ph-like B-ALL.

Birmingham, Alabama
NCT03959085Recruiting· Phase 3
Inotuzumab plus chemotherapy for high-risk childhood leukemia

This Phase 3 trial tests whether adding inotuzumab to standard post-induction chemotherapy improves outcomes for children and young teens with high-risk B-ALL, mixed phenotype acute leukemia (MPAL), or certain high-risk B-LLy. It may help by targeting leukemia cells more directly, but participation depends on specific age, lab results, and medical history rules.

Birmingham, Alabama
NCT05645718Recruiting· Phase 2
Chemo plus targeted antibodies for relapsed childhood B-ALL

This Phase 2 study tests a combination treatment for children, teens, or young adults whose B-cell acute lymphoblastic leukemia (B-ALL) has come back or did not respond to initial therapy. It may help patients who cannot safely receive certain standard medicines like anthracyclines or who cannot tolerate PEG-asparaginase.

Houston, Texas

Hear when a new Acute Lymphoblastic Leukemia, Pediatric trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.