Testing conservative care for people with failing heart pumps
Part of Heart & circulation clinical trials.
This trial is studying a non-surgical (conservative) treatment approach for people being considered for a left ventricular assist device (LVAD). It may help some patients who are too sick or unable to tolerate standard heart failure medicines, but it will only match people with specific heart function and health-test results.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a low heart pumping strength: left ventricular ejection fraction under 35%.
- You have advanced heart failure symptoms (New York Heart Association class III or IV).
- Your blood test shows high brain natriuretic peptide (BNP) over 450 pg/mL.
- You were hospitalized for heart failure within the last 6 months.
- You cannot tolerate usual heart failure medicines (conventional heart failure therapy).
- Your exercise/oxygen test shows low maximum oxygen use (under 12 mL/kg/min).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is testing a special palliative care program to help people with a heart pump (LVAD) feel better and improve their quality of life. If it works, the program could be used to support other LVAD patients in the future.
This trial tests a new left ventricular assist device (LVAD) for people with advanced heart failure who are not responding to standard treatments and are eligible for a heart transplant. The pump helps the heart circulate blood.
This study is testing a heart pump device for people with very advanced heart failure. It's for patients who are very sick and haven't improved with standard treatments. The study will see if this pump is safe and effective.
This study tests a new device or procedure to help people with heart failure and a weak heart pump. If you have a low ejection fraction and are on standard medications, you may be able to join.
This trial tests a left ventricular assist system (a mechanical heart pump for the left side of the heart) in people with very severe heart failure. It may help people who are too sick or not improving despite best available medical treatment.
This trial compares an LVAD device (a pump placed in the chest) plus medicines versus medicines alone for people with advanced, end-stage heart failure. It aims to see which approach works better to help patients live and stay out of the hospital.
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