Clinical trials
Advanced Heart Failure clinical trials
Below are recruiting advanced heart failure clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05250349Recruiting
Ultrasound brain blood flow and thinking in stable heart failure
This trial studies whether a noninvasive ultrasound test of blood flow in the brain, along with memory and thinking questionnaires, can help explain thinking changes in people with stable heart failure. It may help researchers better understand why some people develop cognitive (thinking) difficulties as heart failure progresses.
Krakow, MPAges 18 years+ - NCT07862933Recruiting
AI chat support for older adults with heart failure
This study tests an AI-powered chat system that offers social support to older adults with chronic heart failure. It may help you feel more supported and manage your condition better.
New Taipei City, New Taipei CityAges 60 years+ - NCT06286423RecruitingPhase 4
Colchicine for acute heart failure with low pumping strength
This trial tests if the anti-inflammatory drug colchicine can help people hospitalized with acute heart failure and a weak heart pump. It may benefit those with elevated inflammation markers.
Charlottesville, VirginiaAges 18 years+ - NCT07814612Recruiting
Guided pacing for heart failure with left bundle branch block
This study tests a new way to place a pacemaker lead inside the heart to help it beat more effectively, aiming to improve heart function and symptoms in people with heart failure and a specific electrical problem (left bundle branch block). If you meet the criteria, this could be an option to discuss with your heart doctor.
Nanchang, JiangxiAges 18–80 - NCT07574593Recruiting
Heart Failure Sensor Implant Study
This study tests a small sensor placed in a vein to help monitor and manage heart failure. The sensor tracks fluid buildup in your heart and may help doctors adjust your treatment to keep you feeling better and out of the hospital.
Chula Vista, CaliforniaAges 18 years+ - NCT07560982Recruiting
Improving medication adherence in advanced heart failure
This study looks at whether patients with severe heart failure follow their prescribed medications as recommended by treatment guidelines. The researchers want to understand what helps or prevents patients from taking their medicines correctly, which could improve their heart function and symptoms.
BergamoAges 18–75 - NCT07496372RecruitingPhase 3
Stem cell injection for advanced heart failure
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06773611Recruiting
Heart failure and transplant registry study
This study is creating a registry to track and learn from people with advanced heart failure or who have had a heart transplant. By joining, you help researchers better understand these conditions and improve care.
BolognaAges 18 years+ - NCT07467668Recruiting
Iron infusion for heart failure patients with low iron
This trial tests whether giving intravenous iron to adults hospitalized with heart failure and low iron levels helps improve their health. You may be eligible if you have heart failure with reduced pumping function and low iron stores.
Pleasanton, CaliforniaAges 18 years+ - NCT07405944RecruitingPhase 4
Vericiguat for improving heart function in heart failure
This study tests a medicine called vericiguat (a pill) to see if it can improve the heart's shape and function in people with heart failure and a weakened pump. You would keep taking your usual heart medications plus the study drug.
IzolaAges 18 years+ - NCT07391956Recruiting
Palliative care for advanced heart failure or cancer
This study tests whether special supportive care (called tiered palliative care) can help people with advanced heart failure or certain advanced cancers feel better and have fewer hospital visits. If you live in Manhattan or Queens, speak English or Spanish, and meet the other requirements, you may be able to join.
Astoria, New YorkAges 18 years+ - NCT07252531Recruiting
BrioVAD heart pump study for advanced heart failure
This trial tests a new heart pump (BrioVAD) for people with very advanced heart failure. It aims to help those who are not getting better with standard treatments or who need extra support like IV medicines or a balloon pump.
RotterdamAges 18 years+ - NCT07251894Enrolling by invitation
Meals after heart failure hospitalization
This study provides medically tailored meals to people recently hospitalized with heart failure to see if they help recovery. It is testing whether having healthy meals delivered can improve how patients feel and reduce the chance of being readmitted to the hospital.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07243119Enrolling by invitationPhase 4
Heart failure study with adenosine scans to predict recovery
This trial tests whether high-dose adenosine during a heart scan can better predict how well your heart muscle might recover, compared to standard dosing. The information could help doctors personalize treatment for people newly diagnosed with heart failure and a low ejection fraction.
HerningAges 18–100 - NCT07232030Recruiting
Barostim device for heart failure treatment
This trial tests a device called Barostim, which is implanted under the skin to stimulate nerves that help control heart failure. It's for people with mild to moderate heart failure whose symptoms are not fully controlled by medications.
Mobile, AlabamaAges 18 years+ - NCT06915584Recruiting
Drug management study for heart failure
This study looks at how medications are managed in people with heart failure, especially those who have been in the hospital recently for worsening symptoms. It aims to improve treatment strategies.
Rome, RMAges 18 years+ - NCT05448833Recruiting
Testing a wireless sensor to monitor left heart pressure
This study tests whether a small wireless sensor can safely measure and track pressure in the left upper heart chamber in people with advanced chronic heart failure. It may help the care team better understand pressure changes that are linked to fluid buildup and symptoms, alongside your usual heart medicines.
Petah TikvaAges 22–88 - NCT07023536Recruiting
Heart rehab program from home for chronic heart failure
This trial tests a cardiac telerehabilitation program for people with chronic heart failure. It is designed to see if doing rehab at home using digital tools helps improve health and quality of life.
SalernoAges 18 years+ - NCT06979726RecruitingPhase 4
Lasix under the skin for heart failure symptoms
This study tests a way to give a common water pill (called Lasix, or furosemide) under the skin using a small pump at home, instead of in the hospital. It may help people with heart failure who have fluid buildup that isn't getting better with oral water pills.
Gainesville, FloridaAges 18–80 - NCT06933875Recruiting
Palliative care support for heart failure patients
This study tests a program to bring palliative care (extra support for comfort and quality of life) to people hospitalized with heart failure. Your doctor will take part, and if you qualify, you may get this additional care during your stay.
New Haven, ConnecticutAges 18 years+ - NCT06909682Recruiting
AI monitoring with wearables for chronic heart failure
This trial tests an AI system that uses wearable devices and mini-invasive tools to monitor people with chronic heart failure. The goal is to detect changes early and help manage the condition at home.
SalernoAges 19 years+ - NCT06868797Recruiting
Dapagliflozin for advanced heart failure patients waiting for transplant
This study tests whether dapagliflozin (a medicine already approved for other heart conditions) can help protect kidney and heart function in people with very advanced heart failure who are waiting for a heart transplant. If you qualify, you'll help researchers learn if this drug offers extra benefits beyond standard care.
BronAges 18 years+ - NCT06823583Recruiting
VAD guidance tool testing for patients and clinicians
This study tests a new tool that helps patients prepare for getting a ventricular assist device (VAD), a machine that helps the heart pump blood. Researchers want to see if the tool is easy to use and helpful for both patients and their doctors.
Lincoln, NebraskaAges 19 years+ - NCT06791850Recruiting
Home heart failure support for rural patients and caregivers
This trial tests a home-based palliative care program for people with advanced heart failure living in rural areas and their caregivers. It aims to improve quality of life and reduce symptoms.
Morgantown, West VirginiaAges 45–80
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Common questions
- Are there clinical trials for advanced heart failure?
- Yes. Clin2 currently lists 97 recruiting advanced heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.