Transcatheter valve replacement for badly calcified heart valves
Part of Heart & circulation clinical trials.
This trial tests Prizvalve, a catheter-based procedure to replace a severely damaged “atrioventricular” valve in people at high risk from open-heart surgery. It may help reduce symptoms caused by valve narrowing or leaking when traditional surgery is not a good option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your heart ultrasound shows your atrioventricular valve has moderate or severe calcification and disease (leaking, narrowing, or both)
- You have symptoms and your heart failure symptoms are at least Class II
- You are 18 or older, and you are not pregnant or breastfeeding
- A heart team says a catheter valve replacement could help you and fits your heart anatomy
- You’re likely too high-risk for standard surgery (for example, STS risk above 8%) or you cannot have surgery because of severe valve calcification
- You can understand the study and agree to follow all visits and tests
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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