Testing follow-up chemo and radiation for high-risk breast cancer
Treatments studied
Part of Cancer, Skin clinical trials.
This trial studies a standard follow-up treatment plan that combines chemotherapy and radiation after surgery, and it looks for blood/tissue “biomarkers” that predict who benefits most. If you have high-risk breast cancer that didn’t fully disappear after initial (neoadjuvant) chemo, you may be eligible to help guide better future treatment choices.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older and can sign consent and follow study visits
- You have stage I to IIIB breast cancer and have already had chemo, then surgery (lumpectomy or mastectomy)
- After surgery, there is still leftover cancer at a certain minimum level
- You plan to start radiation within 12 weeks after your last cancer surgery
- Your general health is fairly good (ECOG 0–2) and your blood counts and organs meet lab cutoffs
- You can take the study treatment safely (including heart-function limits if T-DM1 is used) and you are not pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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