Candida autovaccine for adults with jaw yeast infection
Part of Infections, Mouth & dental clinical trials.
This trial tests whether a personalized (autovaccine) treatment called Vacucis Candida can help treat yeast (Candida) infection in the mouth/jaw area. It is for adults who have a history of head-and-neck cancer treatment and currently have Candida confirmed by symptoms and a lab culture.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult (not a minor).
- You had radiation (RT) for head and neck cancer, and it involved the jaws or may have affected them.
- You have signs of Candida yeast infection and a positive culture test.
- Your overall health is stable enough for an autovaccine (no major unstable medical problems).
- Your cancer is stable, meaning there is no active tumor and no uncontrolled spreading or return.
- You are not currently on antifungal medicines for any yeast/fungal infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 1/2 study tests a new cell-based treatment made from a patient’s own fat tissue to improve autoimmune dry mouth (xerostomia). It focuses first on safety, and also looks for early signs that saliva and dry-mouth symptoms may improve.
This Phase 2 study tests a Candida-based vaccine to help stop head and neck squamous cell cancer from coming back after curative treatment. If you are currently cancer-free on scans and exams, the trial may help train your immune system to lower recurrence risk.
This study tests occidiofungin, a new antifungal medication inserted into the vagina twice a week to prevent recurring yeast infections (vulvovaginal candidiasis). The goal is to see if this treatment can stop yeast infections from coming back.
This trial tests if taking a multi-strain probiotic daily can prevent repeat yeast infections in women who have had at least three infections in the past year.
This trial looks for specific signs in your blood and tumor tissue that may show how well immunotherapy is working for recurrent or metastatic head and neck cancer. It aims to help doctors personalize treatment in the future.
This early-phase (Phase 1b) study tests a vaccine designed to train the immune system to fight head and neck squamous cell carcinoma, plus standard immunotherapy. It may help some people by boosting the body’s anti-cancer immune response, but it mainly focuses on safety and finding the best approach.
Hear when a new Radiotherapy; Complications trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.