Dexmedetomidine or propofol for sleep endoscopy in children
Part of Brain & nervous system, Lungs & breathing clinical trials.
This Phase 2 study compares two medicines used to help children sleep during a procedure called drug-induced sleep endoscopy. It’s for children with obstructive sleep apnea who are being evaluated before adenotonsillectomy, to help surgeons understand the cause of the blockage and potentially improve treatment planning.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be a child age 3 to 12 years old
- Have sleep apnea confirmed by an overnight lab sleep test within the last 12 months
- Be someone who could get adenotonsillectomy (tonsils and adenoids surgery), as judged by an ENT specialist
- Be expected to benefit from sleep endoscopy before surgery because of certain risk factors (like severe sleep apnea or obesity)
- Have a parent/guardian who can sign consent and complete forms in English or Spanish
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether muscle stimulation during DISE (a procedure to look at your airway while you’re sedated) can help people with obstructive sleep apnea who can’t tolerate CPAP. Your DISE is part of routine care, and the study adds a muscle stimulation step to see if it changes what’s happening in the throat.
This study compares two sedative medications used during a procedure called drug-induced sleep endoscopy (DISE), which helps doctors see how your airway collapses during sleep. The goal is to find which medication works better and is safer for patients with obstructive sleep apnea.
This trial is testing a new way to guide surgery for children with sleep-disordered breathing (loud snoring or pauses in breathing during sleep). Doctors will use a special camera (endoscopy) to look inside the airway while the child is asleep, to help decide the best surgical treatment.
This trial tests whether using one sleep medicine (propofol) alone works as well as using it with another medicine (dexmedetomidine) for children getting an MRI. The goal is to find the safest and most effective way to help kids stay still during the scan.
This trial studies how well a procedure done while you sleep helps doctors understand the blockage causing obstructive sleep apnea and plan surgery. You may be helped if you’re an adult with sleep apnea who is considering surgical treatment.
This study tests three different medicines to help young children relax before surgery to remove their tonsils and adenoids. It aims to find which medicine works best and is safest for kids ages 2 to 5.
Hear when a new Obstructive Sleep Apnea trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.