Chemo after fully removed pancreatic cancer, guided by gene testing
Treatments studied
Part of Cancer clinical trials.
This Phase 3 study tests whether people with pancreatic cancer should get standard chemo or a chemo plan guided by a tumor gene/RNA test after surgery. It aims to see if the right chemo choice for your tumor biology can improve outcomes after your tumor is removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed pancreatic ductal cancer (including variants) or pancreatic acinar cell cancer, found in tissue tested under a microscope.
- Your surgeon removed the tumor completely (R0 or R1), meaning no visible tumor remains; R2 (incomplete removal) usually does not qualify.
- You must have enough tissue from your surgery available for RNA testing (gene/RNA sequencing).
- You are between 18 and 79 years old and can do normal daily activities with little help (performance status 0–1).
- You have not had chemo or radiation for pancreatic cancer before, and you’ve fully recovered enough to eat well and take chemo without major uncontrolled nausea/vomiting.
- You must meet lab and health thresholds for blood counts, liver/bilirubin, and kidney function, and you must be free from distant spread (no metastases like fluid around lungs/abdomen).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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