Esomeprazole study after gastric bypass and pouch acid levels
Part of Digestive system, Hormones & metabolism clinical trials.
This trial tests how well esomeprazole (a acid-reducing medicine) works after a Roux-en-Y gastric bypass, and how it changes the acidity in the stomach pouch. It may help confirm the best way to control stomach acid after bypass surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a Roux-en-Y gastric bypass with a straight, stapled connection about 12 months ago
- You took proton pump inhibitor medicine routinely for 6 months after your surgery
- You have not taken proton pump inhibitor medicine for at least 4 weeks before the study
- Your upper endoscopy must show no marginal ulcers before the pH monitoring capsule is placed
- You should not have ongoing reflux or ulcer symptoms like burning, regurgitation, or stomach pain
- You must be able to follow study steps and give informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how a one-anastomosis gastric bypass changes how your stomach and esophagus work, especially relating to acid reflux. You may be offered the planned surgery if you fit the weight and heartburn/reflux-related conditions, and the team will measure changes before and after.
This study compares two common weight-loss surgeries (gastric bypass and sleeve gastrectomy) to see which is better at treating acid reflux in people with obesity. If you have reflux and are considering surgery, this trial will randomly put you in one of the two surgery groups.
This study checks whether a surgical “fix” (omentumpexy) can reduce acid reflux after sleeve gastrectomy. It’s mainly for adults having sleeve surgery who have a higher-risk body weight and related health problems.
This trial tests a modified version of sleeve gastrectomy that aims to reduce the risk of acid reflux (GERD) after surgery. It is for people aged 18–65 with a BMI between 35 and 55 who already have some degree of GERD and are planning to have weight loss surgery.
This study tests a new way to treat painful sores (marginal ulcers) that can happen after gastric bypass surgery. Doctors use a special tool (argon plasma) during an endoscopy to help the sores heal faster, and you will get standard ulcer medicine too.
This trial is testing a device called RefluxStop™ that is implanted during keyhole surgery to treat acid reflux (GERD). The study will check how safe and effective the device is for people with long-term GERD, and it aims to help reduce heartburn and other reflux symptoms.
Hear when a new Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.