Clin2
NCT05361174Possibly a fitRecruiting

Testing an IOV-4001 infusion for advanced melanoma or lung cancer

Unresectable MelanomaMetastatic MelanomaStage III Non-small Cell Lung CancerStage IV Non-small Cell Lung Cancer

Part of Cancer, Lungs & breathing, Skin clinical trials.

This trial studies how well and how safely an infusion called IOV-4001 works in adults with advanced melanoma or non-small-cell lung cancer that cannot be removed with surgery. It also aims to see what side effects occur and whether the treatment can help control the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
53 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have advanced melanoma (Stage IIIC/IIID/IV that can’t be removed) or advanced non-small-cell lung cancer (Stage III/IV that can’t be removed)
  • Your prior treatment matches one of the study’s specific rules, including recent progress after certain immunotherapy medicines (anti–PD-1/PD-L1)
  • You can do normal daily activities pretty well (ECOG 0 or 1)
  • Doctors can find at least one spot of cancer that can be measured after a needed procedure for treatment planning
  • Your heart (and sometimes lung) tests meet the trial’s safety limits

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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