Canakinumab for low blood sugar after stomach weight-loss surgery
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests whether canakinumab can reduce frequent low blood sugar episodes after bariatric (weight-loss) surgery. It is designed for people who keep having low blood sugar despite dietary changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had bariatric surgery such as sleeve gastrectomy, Roux-en-Y, omega-loop, or biliopancreatic diversion
- Your low blood sugar has been confirmed (less than 3.0 mmol/L) with at least 5 episodes per week, even after diet changes
- You do not have diabetes by standard medical criteria (including Type 1 or Type 2 diabetes)
- You can use effective birth control if you could become pregnant, and you are not pregnant or breastfeeding
- You are able to follow study visits and procedures, and you can reliably take study treatment as instructed
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This study looks at how food moves through the body and how that may affect episodes of low blood sugar caused by too much insulin. It may help researchers better understand and possibly improve care for people who get hypoglycemia, especially after bariatric (weight-loss) surgery.
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This study looks at how the body handles carbohydrates after eating in people who have had gastric bypass surgery, with or without post-surgery hypoglycemia (low blood sugar). The goal is to understand why some people get low blood sugar after meals and how to better manage it.
This study looks at how the hormone glucagon affects blood sugar in people who have had gastric bypass or sleeve gastrectomy surgery more than a year ago, compared to people who have not had any gastrointestinal surgery. It aims to understand glucose metabolism better and may help improve care for people after bariatric surgery.
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