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NCT07760961Possibly a fitNot yet recruiting

Mizagliflozin for low blood sugar after weight-loss surgery

Postbariatric Hypoglycemia

Part of Digestive system, Hormones & metabolism clinical trials.

This trial tests a medication called mizagliflozin to see if it can reduce episodes of low blood sugar in people who have had gastric bypass surgery. If you experience symptoms like confusion or fainting when your blood sugar drops, this study might help.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
36 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older and had Roux-en-Y gastric bypass surgery more than a year ago.
  • You have had symptoms of low blood sugar (like confusion, seizures, or loss of consciousness) that go away when you eat or drink something sugary, and your blood sugar was below 54 mg/dL during these episodes.
  • You have had at least 4 low blood sugar episodes during a 3-week monitoring period before the study starts.
  • You are not currently taking insulin or certain diabetes medications that increase insulin (like sulfonylureas).
  • You are not currently taking GLP-1 agonists or similar drugs (unless you have stopped them for a wash-out period).
  • You do not have certain heart conditions, recent heart attack, stroke, or active cancer, and you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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