PRP after ACL injury to help prevent knee arthritis
Treatments studied
Part of Injuries & trauma clinical trials.
This study tests whether PRP (platelet-rich plasma) given after an ACL injury and surgery can lower the chance of developing long-term knee arthritis. It may help protect the knee over time by targeting early healing after ACL reconstruction.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your ACL injury happened recently (within 6 weeks of seeing the study team)
- You are between 14 and 50 years old
- You have an ACL injury that will be treated with ACL reconstruction
- You have not had any previous ACL reconstruction surgery
- You have not had PRP, steroid, or hyaluronic acid injections in the last 6 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares standard ACL knee reconstruction using a peroneus longus tendon graft to the same procedure plus an injection of platelet-rich plasma (a concentrated portion of your blood that may help healing). It aims to see if adding the plasma improves knee function after surgery.
This early-phase trial tests a biologic medicine (anakinra) given after an ACL injury to try to prevent or reduce later osteoarthritis (wear-and-tear arthritis). It enrolls young adults who recently tore their ACL and are planning a specific type of ACL reconstruction.
This study tests whether adding a concentrated bone marrow injection during repeat ACL surgery helps healing and recovery better than surgery alone. If you have had a previous ACL reconstruction that failed, you may be eligible.
This trial tests if injecting platelet-rich plasma (a concentration of your own blood platelets) after ACL reconstruction helps with healing and reduces pain. It's for people who recently had ACL surgery and want to try an extra treatment to improve recovery.
This trial tests whether a shot of your own concentrated platelets (PRP) into the knee improves healing after a recent ACL injury. It's for people with mild to moderate ACL tears and no major other knee damage.
This study tests whether platelet-rich plasma (PRP) injections can help knee arthritis in both younger and older adults. If you have knee pain from arthritis and haven't had other treatments recently, you might be able to join.
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