Clinical trials
Anterior Cruciate Ligament Injuries clinical trials
Below are recruiting anterior cruciate ligament injuries clinical trials, each written for real people, not researchers. We’re tracking 119 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05965310Recruiting
Virtual psychology support for ACL repair recovery
This study tests a virtual (online) psychological program to help people recover after ACL ligament surgery. It focuses on first-time ACL repairs and aims to improve how patients cope during recovery.
Detroit, MichiganAges 13 years+ - NCT06974526RecruitingPhase 2
Study of a dissolvable implant for recovery after ACL surgery
This study tests whether a dissolvable implant that releases a medication called oxandrolone can improve recovery after ACL surgery. Oxandrolone may help strengthen the new ligament and speed up healing.
Fortaleza, CearáAges 18–60 - NCT07322497Recruiting
Phone app vs. supervised exercise before ACL surgery
This study compares two ways to exercise before ACL surgery: using a video app on your phone versus doing exercises with a physical therapist. The goal is to see which approach helps you recover better.
Istanbul, KartalAges 18–45 - NCT05527171Recruiting
Virtual reality mindfulness after ACL knee surgery
This study uses a virtual-reality mindfulness meditation program to help improve fear and movement quality after ACL reconstruction. It may help you feel less afraid of movement and land more safely when you return to sports.
Chapel Hill, North CarolinaAges 14–25 - NCT06464705Recruiting
PEMF Therapy for Hamstring Strength After ACL Surgery
This study tests whether wearing a special device (PEMF) for a few minutes each day can help you regain hamstring strength more quickly after ACL surgery. If your hamstring is still weaker than your other leg at 4 months, this may help you recover better.
ShatinAges 18 years+ - NCT07318272Recruiting
ACL surgery repair vs. reconstruction recovery study
This study compares how well people recover after two different types of ACL surgery: reconstruction (using a graft) and primary repair (stitching the torn ligament). It will help doctors understand which approach leads to better knee function long-term. Participants must be between 18 and 40, had their ACL surgery at Gazi University, and be at least one year past surgery.
Ankara, ÇankayaAges 18–40 - NCT07580157Enrolling by invitation
Shockwave therapy for knee pain after ACL surgery
This study tests whether focused shockwave treatment can reduce knee pain in people who have had ACL (anterior cruciate ligament) reconstruction surgery. Shockwave therapy uses sound waves to reduce pain and inflammation.
Rochester, MinnesotaAges 18 years+ - NCT06493851Recruiting
Hyperbaric oxygen therapy to speed recovery after ACL reconstruction
This trial tests whether hyperbaric oxygen therapy (breathing oxygen in a pressurized chamber) can help you recover faster after ACL knee surgery. If you're having ACL reconstruction, this treatment might reduce healing time.
ZrifinAges 18–45 - NCT06538792Recruiting
Proprioception and strength after ACL reconstruction
This study looks at how well people regain body awareness, muscle strength, and fear of movement after ACL knee surgery. It may help understand recovery patterns in the first year after surgery.
IstanbulAges 18–35 - NCT06259968Recruiting
Electrical stimulation after ACL surgery recovery trial
This trial tests if adding electrical stimulation to standard physical therapy helps people recover strength and movement after ACL reconstruction surgery. It compares two rehab programs starting within days after surgery.
Veranópolis, Rio Grande do SulAges 18–40 - NCT03552705RecruitingPhase 2
Tranexamic acid to reduce knee inflammation after ACL injury
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
Stanford, CaliforniaAges 18–30 - NCT06099600Recruiting
ACL reconstruction study with follow-up via app
This trial is for people getting ACL (anterior cruciate ligament) surgery. It tests if tracking your recovery through questionnaires on a phone or tablet helps improve outcomes.
LyonAges 18 years+ - NCT07090616Recruiting
Comparing two knee braces after ACL surgery
This study compares two different knee braces used after ACL surgery to see which one helps people recover better. If you are having your first ACL reconstruction, you may be able to join and help find out if one brace works better than the other.
Chicago, IllinoisAges 18 years+ - NCT06905691Recruiting
Eccentric training after ACL reconstruction
This study tests if a specific exercise (eccentric training) helps people recover better after ACL surgery. You may join if you are between 18 and 40 and are scheduled for this surgery.
Veranópolis, Rio Grande do SulAges 18–40 - NCT06762392Recruiting
Blood flow restriction for ACL rehab: a pilot study
This study tests whether using a special band that slightly restricts blood flow (blood flow restriction) during rehabilitation can help people recover better after ACL knee surgery. It's a small early study to see if this method is safe and effective.
Valencia, ValenciaAges 18 years+ - NCT07523854Recruiting
Knee Strength Recovery After ACL Surgery: Comparing Graft Types
This study compares how well the knee recovers its strength after ACL (anterior cruciate ligament) reconstruction surgery using two different graft options. By tracking your progress over time, researchers hope to understand which graft type helps you regain the most strength.
AnkaraAges 13–45 - NCT07411625Recruiting
Pre-surgery exercise program for ACL injury patients
This trial tests whether doing special exercises before ACL surgery (called prehabilitation) helps you recover better after the operation. It's for people who have a first-time ACL tear and are scheduled for reconstruction surgery using a tendon from their own body.
NantesAges 18 years+ - NCT07185802Recruiting
PRP injection for recent ACL injury
This trial tests whether a shot of your own concentrated platelets (PRP) into the knee improves healing after a recent ACL injury. It's for people with mild to moderate ACL tears and no major other knee damage.
DhakaAges 18–50 - NCT06972914Enrolling by invitation
Brace wearing time after ACL surgery recovery study
This trial tests how long patients should wear a brace after anterior cruciate ligament (ACL) reconstruction surgery. It aims to find the best duration for faster short-term recovery.
Chongli, HebeiAges 18 years+ - NCT07115316Recruiting
Hamstring exercises with physiotherapy for football players with mild ACL injury
This study tests if adding special hamstring exercises to standard physiotherapy can help young football players recover better after a mild ACL tear. It focuses on improving sports performance and quality of life with no surgery needed.
Ras al-Khaimah, Emirate of Ras Al KhaimahAges 19–25 - NCT07243535Recruiting
Rhythm training for athletes after ACL surgery
This study compares two types of rhythm-based training (fractal vs isochronous cueing) to see which helps athletes regain better movement after ACL reconstruction. If you're an athlete who had ACL surgery less than two years ago and are now pain-free walking, you may be able to join.
Almada, Monte de CaparicaAges 15–35 - NCT07671235Recruiting
Comparing graft options for repeat ACL surgery
This study compares two types of tissue grafts (your own or a donor's) used in a second ACL knee surgery to see which leads to better outcomes and fewer failures over at least two years.
Bologna, BolognaAges 18–50 - NCT05584020Recruiting
ACL repair vs. reconstruction for a recent tear
This study compares two ways to repair a torn ACL: stitching it back together (repair) versus using a graft from another tendon (reconstruction). It is for people who have a fresh, uncomplicated ACL tear and want to see which approach works better.
Hangzhou, ZhejiangAges 18 years+ - NCT03968913RecruitingEarly Phase 1
Biologic shot to prevent knee arthritis after ACL injury
This early-phase trial tests a biologic medicine (anakinra) given after an ACL injury to try to prevent or reduce later osteoarthritis (wear-and-tear arthritis). It enrolls young adults who recently tore their ACL and are planning a specific type of ACL reconstruction.
Los Angeles, CaliforniaAges 18–35
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Anterior Cruciate Ligament Injuries trials by city
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Anterior Cruciate Ligament Injuries trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for anterior cruciate ligament injuries?
- Yes. Clin2 currently lists 119 recruiting anterior cruciate ligament injuries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament injuries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament injuries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Reconstruction
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Tear
- Anterior Cruciate Ligament (ACL) Tear
- Anterior Cruciate Ligament
- Anterior Cruciate Ligament (ACL) Reconstruction
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.