Testes less radiation after a complete response to medicines
Part of Cancer, Skin clinical trials.
This study checks whether some people with breast cancer who have no remaining cancer after medicine (neoadjuvant systemic therapy) can safely receive less radiation. It may help reduce side effects while still keeping cancer controlled.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re a woman age 18 or older
- Your breast cancer is hormone receptor positive (HR+) and HER2 negative, or HER2 positive, or triple-negative
- Your initial breast tumor was small to medium (clinical stage T1–2) and it was unifocal (one main area)
- Before starting treatment, your lymph nodes looked clear (confirmed by ultrasound or FDG-PET/CT)
- You received medicines before surgery, had a marker placed in the tumor, and had breast-conserving surgery (no mastectomy)
- After treatment, scans/pathology showed complete response: no cancer cells or DCIS in the breast and lymph nodes
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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