Metformin to protect the optic nerve in glaucoma
Treatments studied
Part of Eyes & vision clinical trials.
This study tests whether metformin can slow damage to the optic nerve in people with glaucoma. It uses eye scans and vision tests to look for changes over time, aiming to help preserve sight.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older
- Have clear enough vision in at least one eye (best corrected vision of 20/40 or better)
- Have eye pressure no higher than 24 during screening and at the start of the study
- Show evidence of worsening optic-nerve thinning on eye scan results in at least one eye over the last 3 years
- Be able to do reliable visual field testing (vision field test) and provide good-quality scan images
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether NAD precursor supplements can improve nerve health and vision in people with glaucoma. If you have glaucoma with mild to moderate vision loss, this study may help understand if these supplements could protect your optic nerve.
This Phase 1 study tests an insulin-based eye treatment to see if it’s safe and potentially helpful for people with glaucoma-related optic nerve damage. If you may be eligible, you’ll have a close eye exam and repeated vision testing, mainly focused on one study eye.
This trial tests whether a dietary supplement (DHA + citicoline) can help protect vision in people with glaucoma. You may qualify if you have confirmed glaucoma in at least one eye and are between 50 and 75 years old.
This trial studies whether nicotinamide (a form of vitamin B3/niacin) can slow or affect glaucoma progression. You may be eligible if you have newly diagnosed, untreated glaucoma or if you have treated glaucoma with measurable visual field changes.
This trial tests whether a vitamin B3 supplement called nicotinamide can help slow down vision loss in people with glaucoma. It is for those with moderate disease who are already on treatment.
This study looks at different ways to measure how glaucoma affects your vision over time by comparing visual field results. It may help researchers find better models to track progression so treatment decisions can be made more accurately.
Hear when a new Glaucoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.