Liver-first treatment study for colorectal cancer spread to liver
Part of Cancer, Digestive system clinical trials.
This trial studies a “liver-first” approach for colorectal cancer that has spread mainly to the liver, to see if it can help more people have the tumor(s) removed or treated. You may be eligible if your liver involvement is too extensive for immediate surgery but could become treatable after a specific plan.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your colorectal cancer has spread mainly to the liver and your liver tumor area is under a certain size (FLR under 30%, or under 40% if your liver was damaged by chemotherapy)
- You are 18 or older and can understand the study and sign consent
- Your main liver tumors must be potentially removable or treatable (not clearly hopeless to remove/treat), based on your care team’s plan
- If you have lung or brain metastases, they must be removable or treatable (able to be removed or ablated) as decided by a tumor board
- You should not have cancer spread outside the liver that cannot be removed or treated
- You should not be pregnant or breastfeeding, and pregnancy prevention rules must be followed if you could become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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