Clin2
NCT06185556Possibly a fitRecruiting

New treatments for liver tumors near blood vessels or bile ducts

Colorectal CancerLiver MetastasesLiver Metastasis Colon CancerUnresectable Solid Tumor

Part of Cancer, Digestive system clinical trials.

This trial tests two procedures—irreversible electroporation and stereotactic body radiotherapy—for people whose colorectal cancer has spread to the liver (1–3 tumors near major blood vessels or bile ducts) and can't be surgically removed or treated with heat. The goal is to see if these approaches can safely destroy those hard-to-reach tumors.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
78 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have colorectal cancer that has spread to the liver (1–3 tumors, each 0–5 cm) close to a major blood vessel or bile duct, making surgery or heat treatment not possible.
  • You may have a few more liver tumors (up to 10 total), as long as they can be removed or treated with other methods.
  • You may have limited cancer outside the liver (only 1 spot allowed in certain areas).
  • You had a liver-focused treatment before, and it's okay to have received chemotherapy before starting the trial.
  • You are at least 18 years old, have adequate organ function, and are classified as ASA 0–3 (generally healthy to mild/moderate health issues).
  • You cannot have certain types of active or progressing cancer, uncontrolled high blood pressure, or heart conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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