Local liver treatment for colorectal cancer that has spread
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests whether treating liver tumors with surgery or ablation can help people whose colorectal cancer has spread to the liver and other organs. It may be an option if you've had only 1 or 2 types of chemotherapy and your non-liver metastases are stable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 80 years old.
- Your colorectal cancer has spread to both the liver and at least one other organ (like lungs or lymph nodes), and the non-liver spots are stable.
- You've had only first- or second-line systemic therapy (chemotherapy or targeted drugs).
- Your liver tumors can be completely removed by surgery or destroyed by ablation (up to 5 tumors, each 3 cm or smaller).
- Your liver function is good (Child-Pugh score 7 or lower) and your overall health is fair (ECOG 0-1).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether treating all liver tumors with surgery, ablation, or radiation is better than continuing standard chemotherapy for people with colorectal cancer that has spread only to the liver. It's for those whose liver tumors have been controlled by initial chemotherapy and are considered removable.
This trial compares two surgical approaches for removing liver metastases from colon cancer: anatomical resection versus nonanatomical resection. It aims to see which approach works better for people whose tumors have certain genetic changes or are on the right side of the colon.
This trial compares two ways to treat colorectal cancer that has spread to the liver: removing liver tumors with surgery versus destroying them in place with local ablation. It may help doctors learn which approach works best for people whose disease can be fully treated and who have enough healthy liver left.
This trial tests a combination treatment that uses heat or cold (ablation) to destroy liver tumors along with medicines that boost your immune system to fight cancer. It is for people whose colorectal cancer has spread to the liver and who could not have surgery, or whose first treatment stopped working.
This study looks at whether a liver transplant can help people whose colorectal cancer has spread to the liver but cannot be removed by surgery. It also checks whether certain cancer features, treatment history, and blood/health status make transplant safer or more effective.
This study tests a local (targeted) approach for breast cancer that has spread to the liver. It looks at whether treating liver metastases with planned liver surgery, along with standard cancer treatment before and after, can improve outcomes.
Hear when a new Metastatic Colorectal Carcinoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.