Study how depression and cannabis affect the brain in young adults with HIV
Part of Infections, Mental health clinical trials.
This study looks at brain activity to understand how depression and cannabis use may be linked in young adults living with HIV. It mainly involves questionnaires, mental health screening, and brain scans, which may help researchers better understand risk factors and brain “underpinnings.”
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 39 years old
- You have confirmed HIV infection and can show proof from records or testing
- You can speak and understand English or Spanish, and you can follow study steps (an IQ score above 75 is required)
- You either have depression symptoms, or you do not—either way, you must fit the study’s depression/cannabis group rules
- If you use cannabis: you used cannabis often (at least 20 of the last 30 days) and your urine test must show THC
- You must be able to safely do MRI scans (for example, no pacemaker/metal in body, and not severe claustrophobia)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how cannabis affects the brain and mood in teens and young adults. It compares people who use cannabis, people with depression who don't use cannabis, and healthy volunteers to understand links between cannabis use and mental health.
This study looks at how depression and its treatment may affect the brain and immune-related body systems in people with HIV. You may be eligible if you have depression and a well-controlled HIV viral load, and you can safely complete brain MRI scans.
This study tests a program that helps people with HIV manage depression and stick to their treatment. It's for adults in Cape Town, South Africa, who have a detectable HIV viral load or may have one, and who show signs of depression.
This study looks at whether ongoing marijuana use changes “brain inflammation” and brain cell injury in people living with HIV. It may help researchers understand potential risks or protective effects and how treatment and brain health interact.
This Phase 2 study tests whether cannabidiol (CBD) and tetrahydrocannabinol (THC) change the gut microbiome and brain-related inflammation in people with HIV. It may help researchers understand new ways to reduce inflammation, but you would need strict cannabis and CBD/THC avoidance during the study.
This study uses brain scans to understand how stimulant use affects the brain in people with HIV who are on treatment. It may help find ways to improve brain health.
Hear when a new Depression trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.