Clin2
NCT05136703Possibly a fitRecruiting

Study depression treatment effects in people living with HIV

DepressionHIV-1-infectionInflammation

Part of Immune system & allergy, Infections, Mental health clinical trials.

This study looks at how depression and its treatment may affect the brain and immune-related body systems in people with HIV. You may be eligible if you have depression and a well-controlled HIV viral load, and you can safely complete brain MRI scans.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
150 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years old or older
  • You can read and speak English
  • You have HIV and are taking HIV medications under your own name
  • You currently have major depression (by a structured interview or depression score 7+)
  • If you take antidepressants, your dose has been the same for at least 2 months
  • Your HIV viral load is under 200 copies/mL and you can safely have an MRI scan

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05453513Recruiting
Study how depression and cannabis affect the brain in young adults with HIV

This study looks at brain activity to understand how depression and cannabis use may be linked in young adults living with HIV. It mainly involves questionnaires, mental health screening, and brain scans, which may help researchers better understand risk factors and brain “underpinnings.”

Miami, Florida
NCT07032363Recruiting
Depression and HIV treatment support study

This study tests a program that helps people with HIV manage depression and stick to their treatment. It's for adults in Cape Town, South Africa, who have a detectable HIV viral load or may have one, and who show signs of depression.

Miami, Florida
NCT05849038Recruiting· Phase 2
Treating inflammation to improve depression in HIV

This Phase 2 study looks at whether lowering inflammation can help improve depression symptoms in adults living with HIV. You may be able to join if your HIV is well controlled and you are currently experiencing major depression (or a certain type of bipolar depression).

Atlanta, Georgia
NCT06814275Recruiting
Brain health study for HIV+ stimulant users

This study uses brain scans to understand how stimulant use affects the brain in people with HIV who are on treatment. It may help find ways to improve brain health.

Winston-Salem, North Carolina
NCT07080138Not yet recruiting
HIV emotional health study

This study looks at the mental and emotional well-being of people living with HIV. It aims to understand how patients feel and what support they may need.

NCT04810858Recruiting
Study how chronic marijuana affects brain inflammation in HIV

This study looks at whether ongoing marijuana use changes “brain inflammation” and brain cell injury in people living with HIV. It may help researchers understand potential risks or protective effects and how treatment and brain health interact.

Winston-Salem, North Carolina

Hear when a new Depression trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.