Testing efinetakin and pembrolizumab for recurrent glioblastoma
Treatments studied
Part of Cancer clinical trials.
This Phase 2 trial studies efinetakin alfa plus pembrolizumab for adults with recurrent glioblastoma (a fast-growing brain tumor). It aims to shrink or control the tumor and help patients live longer and better after standard treatments like surgery, radiation, and temozolomide.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- Your glioblastoma must be confirmed from a past biopsy or surgery, and it must have progressed or returned.
- You need an MRI showing a tumor area that your neurosurgeon can biopsy or remove at Mayo Clinic in Rochester, Minnesota.
- You must be well enough to take part (ECOG 0–1 and KPS 70 or higher).
- Your blood counts and organ tests (kidney, liver, and clotting) must be in safe ranges from bloodwork done within 15 days of starting treatment.
- You must be willing to use birth control (if applicable) and agree to provide tumor tissue and blood samples for research.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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