Testing serotonin blockers after a first heart attack
Part of Heart & circulation clinical trials.
This Phase 2 trial tests whether blocking serotonin receptors can help after a first heart attack that has caused a specific type of leaking mitral valve problem. It aims to see if the treatment improves heart function and heart-valve measurements while keeping patients safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old
- You had your first STEMI heart attack, and it was confirmed with blocked coronary arteries
- Your heart pumping strength (left ventricle ejection fraction) is below certain thresholds and you have evidence of mitral valve “tethering/tenting” or specific heart muscle movement changes
- You must be able to give informed consent and be medically stable (not in shock)
- You have not had prior mitral valve surgery or procedures
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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