Clin2
NCT05475925Possibly a fitRecruiting

Test drug DR-01 for specific blood cancer types

LGLL - Large Granular Lymphocytic LeukemiaPrimary Cutaneous Gamma-Delta T-Cell LymphomaPrimary Cutaneous CD8+ Aggressive Epidermotropic T-Cell LymphomaHepatosplenic T-cell LymphomaSubcutaneous Panniculitis-Like T-Cell LymphomaAggressive NK Cell LeukemiaSystemic EBV1 T-cell Lymphoma, if CD8 PositiveHydroa Vacciniforme-Like Lymphoproliferative Disorder

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This early-phase study tests DR-01 to treat large granular lymphocytic leukemia (LGLL) or certain aggressive T-cell or cytotoxic lymphomas. It aims to see whether the drug is safe and can shrink or control the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
200 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be at least 18 years old and be able to sign consent and follow study visits.
  • You must have adequate heart, blood clotting, and organ function on screening tests.
  • If you can become pregnant, you must use highly effective birth control starting now and continuing through at least 12 months after the last dose.
  • If you are able to father a pregnancy, you must agree to use effective birth control during the study.
  • You must have stopped at least one prior cancer treatment (for the LGLL group).
  • You must meet the specific diagnosis and measurable disease rules for the lymphoma group (including scans and/or biopsy).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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