Steroid treatment for children with ITP to raise platelets
Treatments studied
Part of Blood & lymphatic, Immune system & allergy clinical trials.
This trial studies a short, high-dose steroid plan (prednisone plus dexamethasone) to treat immune thrombocytopenia (ITP) in children and raise low platelet counts. It may help reduce bleeding risk while using an approach tested in children soon after diagnosis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- The child has been diagnosed with ITP within the last 3 months
- Age is more than 28 days old and 14 years old or younger
- Platelets are very low: under 20, or under 30 after 1 week of IVIG treatment
- The parent or guardian can sign informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug called anti-CD38 antibody for children and teens with chronic immune thrombocytopenia (ITP) whose platelet counts remain low despite other treatments. It may help increase platelet counts and reduce bleeding risk.
This trial compares two treatments for pregnant women with ITP (immune thrombocytopenia) and low platelet counts. It tests whether adding IVIg (immune globulin) to standard prednisone (steroid) therapy is more effective than prednisone alone.
This trial tests a new antibody treatment (anti-CD38) for children ages 6 to 18 who have had low platelets for at least 3 months and did not improve with steroids. The goal is to see if this treatment can safely raise platelet counts.
This trial tests a combination of upadacitinib (a pill that calms the immune system) and high-dose dexamethasone (a steroid) as the first treatment for adults with newly diagnosed immune thrombocytopenia (ITP). It aims to see if this mix can safely raise platelet counts better than steroids alone.
This trial tests how many cycles of high-dose dexamethasone (a steroid) work best for adults newly diagnosed with ITP, a condition that causes low platelets and bruising or bleeding. The goal is to find the right dose schedule to safely raise platelet counts.
This study looks at why some children with immune thrombocytopenic purpura (a condition where the immune system mistakenly destroys platelets) do not respond well to steroid treatment. The goal is to find better ways to care for children who have this problem.
Hear when a new Immune Thrombocytopenia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.