Metformin for adult myotonic dystrophy type 1 muscle weakness
Part of Bones, joints & muscles, Brain & nervous system, Genetic & congenital clinical trials.
This Phase 3 trial tests whether metformin can improve symptoms and safety in adults with genetically confirmed myotonic dystrophy type 1 (DM1). It may help reduce muscle problems, but you must meet specific walking, breathing, heart, and kidney requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have DM1 confirmed by genetic testing
- You are age 18 to 70 (men or women)
- You can still walk with at most stick/cane-type help
- Your mobility score (MIRS) is 3 or 4
- If you can have a pregnancy, you can use effective birth control during the study
- You can provide consent and you are enrolled through your social security system
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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