Clin2
NCT06260033Possibly a fitRecruiting

Radiation Therapy for Oligoprogressive ER+ Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8Estrogen Receptor-Positive Breast CarcinomaMetastatic Breast Carcinoma

Part of Cancer, Skin clinical trials.

This trial tests whether a precise radiation treatment (SBRT) can target a few growing spots of estrogen receptor-positive breast cancer that has spread to other parts of the body. It also uses a special PET scan (FES PET/CT) to see how well the cancer responds. The goal is to slow down the cancer and delay the need for stronger treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
18 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have estrogen receptor-positive (ER+) breast cancer that has spread to other parts of the body.
  • You have 1 to 4 spots of cancer that are growing and can be treated with a precise type of radiation called stereotactic body radiation therapy (SBRT).
  • You have had between 1 and 3 types of treatment for the cancer that has spread.
  • You are able to read and understand English or Spanish for questionnaires.
  • You are willing to use birth control if you or your partner could become pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05534438Recruiting· Phase 2
Tested targeted radiation plus usual drug treatment in metastatic breast cancer

This Phase 2 study tests whether adding a very focused type of radiation to standard drug treatment can better control metastatic breast cancer. It is for people whose cancer is only progressing in one spot, seen on a PET scan.

Basking Ridge, New Jersey
NCT05830058Recruiting· Phase 2
PET-guided focused radiation for limited worsening lung, melanoma, kidney cancer

This Phase 2 study tests whether using a PET scan to guide focused radiation (SBRT) can control a small number of cancer spots that are starting to grow despite prior treatment. It may help patients avoid wider radiation by targeting only the limited progressing areas.

Duarte, California
NCT05733949Recruiting· Early Phase 1
Targeted radiation for people with many solid tumor metastases

This trial tests a precise type of radiation that targets multiple tumor spots in a carefully planned way. It may help people with many metastatic (spread) solid tumors when standard treatments aren’t working or can’t be used.

Duarte, California
NCT06925984Recruiting
Targeted radiation for breast cancer that has spread and is growing a little

This trial tests whether giving focused, high-dose radiation to spots where the cancer is growing can help control the disease while you stay on your current hormone therapy and/or CDK4/6 inhibitor. It is for people with ER+/HER2- breast cancer that has spread to a few places and is slowly starting to progress.

Brussels
NCT06489821Not yet recruiting
Radiation for limited cancer spread in advanced breast cancer

This trial tests whether targeted radiation can control a few growing spots of breast cancer while the rest of the cancer stays stable on your current treatment. It aims to delay the need to switch to a new therapy.

NCT06882499Not yet recruiting
Focused radiation for breast cancer that is mostly stable

This study tests whether giving focused radiation (SABR) to a few growing spots of breast cancer, while continuing your current hormone therapy and CDK 4/6 inhibitor, can help control the cancer longer than switching to a different treatment. It is for people whose cancer is mostly stable but has a small number of spots that have started to grow.

Hear when a new Anatomic Stage IV Breast Cancer AJCC v8 trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.